ReviewBritish dental journal2018
Beyond Streptococcus mutans: clinical implications of the evolving dental caries aetiological paradigms and its associated microbiome.
Review in British dental journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.
- Microbial colonisation associated with conventional and self-ligating brackets: a systematic review.Journal of orthodontics · 2022Pooled it
- Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis.Medical science monitor : international medical journal of experimental and clinical research · 2022Trial
- Recent Advances in Caries Prevention and Non-Invasive Management: From Ecological Modulation to Precision Interventions.Dentistry journal · 2026Review
- Effects of Acidic Exposure on Surface Properties and Bacterial Adhesion of Three Resin-Based CAD/CAM Materials.Polymers · 2026Article
- The in-vitro effect of bovine milk, and plant-based alternatives on oral microorganisms and biofilms.Scientific reports · 2026Article
- Prevalence of oral streptococci and glucosyltransferase genes in mother-child pairs: a cross-sectional study in Turkish families.BMC pediatrics · 2026Article
- Illuminating the invisible: translational biophotonics for contemporary caries detection and biological decision-making.Frontiers in oral health · 2026Review
- Microbial changes in different parts of the oral cavity during the early stage of clear aligner treatment: a preliminary study.Clinical oral investigations · 2025Article
- The MutRS quorum-sensing system controls lantibiotic mutacin production in the human pathogenProceedings of the National Academy of Sciences of the United States of America · 2025Article
- A novel stable biomimetic adhesive coating for functionalization of orthodontic brackets against bacterial colonization and white spot lesions.BMC oral health · 2025Article
- Hydrogen-rich electrolyzed water is a useful mouthwash due to its biofilm-control properties: an in vitro and in vivo study.Journal of Yeungnam medical science · 2025Article
- Article
- The Hall technique: knowledge, practice, and concerns of dentists in primary care settings in the State of Qatar-a questionnaire-based survey.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- Review
- qPCR assay optimisation for a clinical study comparing oral health risk in Rett syndrome.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- Advanced Dental Care: β-Chitosan Zinc Oxide Nanoparticles Targeting Cariogenic Microorganisms.Cureus · 2024Article
- Longitudinal Microbiome Changes in Supragingival Biofilm Transcriptomes Induced by Orthodontics.JDR clinical and translational research · 2024Article
- Pine-Oil-Derived Sodium Resinate Inhibits Growth and Acid Production ofDentistry journal · 2024Article
- Plaque Microbiome in Caries-Active and Caries-Free Teeth by Dentition.JDR clinical and translational research · 2024Article
- The microbiome of African penguins (Spheniscus demersus) under managed care resembles that of wild marine mammals and birds.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aetiological concepts of dental caries have evolved over the years from being considered as a disease initiated by nonspecific microorganisms, to being regarded as an 'infectious' disease caused by specific bacteria, to the current paradigms that emphasise a 'mixed bacterial-ecological approach' as being responsible for lesion initiation and pathogenesis. These aetiological paradigms are not just intellectual concepts but have important implications on how clinicians manage this age-old disease in the twenty-first century. Despite evidence-backed recommendations for adopting more biological measures to counter the disease, a significant proportion of dentists continue following traditional caries management guidelines in their daily clinical practice. This paper will review the evolving dental caries aetiological concepts and highlight the current evidence for adopting a more ecological approach to caries prevention, risk assessment, and treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.