Evidence map›Paper›PMID 29449619›Full record

ArticleScientific reports2018

Chronic ET

Xiaomei Guo, Huan Chen, Ling Han, Stephan Haulon, Ghassan S Kassab

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Aqueous extract ofFrontiers in pharmacology · 2023
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Xiaomei GuoCalifornia Medical Innovations Institute, San Diego, California, USA.
Huan ChenCalifornia Medical Innovations Institute, San Diego, California, USA.
Ling HanCalifornia Medical Innovations Institute, San Diego, California, USA.
Stephan HaulonAortic Center, Hôpital Marie Lannelongue, Le pLessis Robinson, Université Paris Sud, Clemenceau, 91400, Orsay, France.
Ghassan S KassabCalifornia Medical Innovations Institute, San Diego, California, USA. gkassab@calmi2.org.
California Medical Innovations Institute · USHypertension pulmonaire : physiopathologie et innovation thérapeutique · FRLaboratoire Analyse, Géométrie et Applications · FR

Funding

Micro-Mechanical Role of Hypertension in Intimal HyperplasiaR01HL117990 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI KASSAB, GHASSAN S · 2013 to 2016
$2.4M
NHLBI NIH HHS R01 HL117990
6 · The paper itself

Abstract

Arterial stiffness may contribute to the pathogenesis of hypertension. The goal of this study is to elucidate the role of Endothelin-1 (ET-1) in aortic stiffening-induced hypertension through ET

Indexed as

AnimalsAortaArteriesBlood PressureEndothelin-1FemaleHemodynamicsHypertensionMalePulse Wave AnalysisRatsRats, WistarVascular StiffnessEndothelin-1

Identifiers

PMID29449619
PMCPMC5814460
OpenAlexW2805965305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.