Evidence map›Paper›PMID 29449606›Full record

ArticleScientific reports2018

Human subarachnoid space width oscillations in the resting state.

Marcin Gruszecki, Gemma Lancaster, Aneta Stefanovska, J Patrick Neary, Ryan T Dech, Wojciech Guminski, Andrzej F Frydrychowski, Jacek Kot, Pawel J Winklewski

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcin GruszeckiDepartment of Radiology Informatics and Statistics, Medical University of Gdansk, Gdansk, Poland. mgruszecki@gumed.edu.pl.
Gemma LancasterDepartment of Physics, Lancaster University, Lancaster, UK.
Aneta StefanovskaDepartment of Physics, Lancaster University, Lancaster, UK.ORCID 0000-0001-6952-8370
J Patrick NearyFaculty of Kinesiology and Health Studies, University of Regina, Regina, Canada.
Ryan T DechFaculty of Kinesiology and Health Studies, University of Regina, Regina, Canada.
Wojciech GuminskiDepartment of Computer Communications, Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, Gdansk, Poland.
Andrzej F FrydrychowskiDepartment of Human Physiology, Medical University of Gdansk, Gdansk, Poland.
Jacek KotNational Centre for Hyperbaric Medicine, Institute of Maritime and Tropical Medicine, Medical University of Gdansk, Gdynia, Poland.ORCID 0000-0001-5604-8407
Pawel J WinklewskiDepartment of Human Physiology, Medical University of Gdansk, Gdansk, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal cerebrospinal fluid (CSF) pulsatility has been implicated in patients suffering from various diseases, including multiple sclerosis and hypertension. CSF pulsatility results in subarachnoid space (SAS) width changes, which can be measured with near-infrared transillumination backscattering sounding (NIR-T/BSS). The aim of this study was to combine NIR-T/BSS and wavelet analysis methods to characterise the dynamics of the SAS width within a wide range of frequencies from 0.005 to 2 Hz, with low frequencies studied in detail for the first time. From recordings in the resting state, we also demonstrate the relationships between SAS width in both hemispheres of the brain, and investigate how the SAS width dynamics is related to the blood pressure (BP). These investigations also revealed influences of age and SAS correlation on the dynamics of SAS width and its similarity with the BP. Combination of NIR-T/BSS and time-frequency analysis may open up new frontiers in the understanding and diagnosis of various neurodegenerative and ageing related diseases to improve diagnostic procedures and patient prognosis.

Indexed as

Pulsatile FlowAdolescentAdultBlood Flow VelocityBlood PressureCerebrospinal FluidCerebrovascular CirculationFemaleHealthy VolunteersHeart RateHumansHypertensionMaleMultiple SclerosisSpectroscopy, Near-InfraredSubarachnoid Space

Identifiers

PMID29449606
PMCPMC5814422

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.