Evidence map›Paper›PMID 29449574›Full record

ArticleBlood cancer journal2018

Upregulation of FOXM1 in a subset of relapsed myeloma results in poor outcome.

Chunyan Gu, Carol Holman, Ramakrishna Sompallae, Xuefang Jing, Michael Tomasson, Dirk Hose, Anja Seckinger, Fenghuang Zhan, Guido Tricot, Hartmut Goldschmidt and 2 more

Abstract readLetter
In one paragraph

Article in Blood cancer journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. FOXM1 promotes hepatocellular carcinoma progression by regulating KIF4A expression.Journal of experimental & clinical cancer research : CR · 2019
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chunyan GuThe Third Affiliated Hospital, Nanjing University of Chinese Medicine, 210023, Nanjing, China.
Carol HolmanDepartment of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, 52242, Iowa, USA.
Ramakrishna SompallaeDepartment of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, 52242, Iowa, USA.
Xuefang JingDepartment of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, 52242, Iowa, USA.
Michael TomassonDepartment of Internal Medicine, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, 52242, Iowa, USA.
Dirk HoseMedizinische Klinik V, Universitätsklinikum Heidelberg, 69120, Heidelberg, Germany.
Anja SeckingerMedizinische Klinik V, Universitätsklinikum Heidelberg, 69120, Heidelberg, Germany.
Fenghuang ZhanDepartment of Internal Medicine, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, 52242, Iowa, USA.
Guido TricotDepartment of Internal Medicine, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, 52242, Iowa, USA.
Hartmut GoldschmidtMedizinische Klinik V, Universitätsklinikum Heidelberg, 69120, Heidelberg, Germany.
Ye YangThe Third Affiliated Hospital, Nanjing University of Chinese Medicine, 210023, Nanjing, China. yangye876@sina.com.
Siegfried JanzDepartment of Pathology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, 52242, Iowa, USA. siegfried-janz@uiowa.edu.ORCID http://orcid.org/0000-0002-2229-5511

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Mark E Burkard · 2000 to 2026
$70.0M
Defining genetic pathways of plasma-cell neoplasiaR01CA151354 · NCI · UNIVERSITY OF IOWA · PI JANZ, SIEGFRIED · 2010 to 2022
$3.9M
NEK2 Over-expression Causes Drug Resistance in MyelomaR01CA152105 · NCI · UNIVERSITY OF UTAH · PI ZHAN, FENGHUANG · 2010 to 2014
$1.5M
Validation of FOXM1 as a new therapeutic target in high-risk myelomaR21CA187388 · NCI · UNIVERSITY OF IOWA · PI JANZ, SIEGFRIED · 2016 to 2017
$365k
NCI NIH HHS P30 CA086862NCI NIH HHS R01 CA151354NCI NIH HHS R01 CA152105NCI NIH HHS R21 CA187388
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, NeoplasticMultiple MyelomaUp-RegulationFemaleFollow-Up StudiesForkhead Box Protein M1HumansMaleNeoplasm ProteinsRecurrenceForkhead Box Protein M1FOXM1 protein, humanNeoplasm Proteins

Identifiers

PMID29449574
PMCPMC5814454

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.