SynthesisScientific reports2018
Common surgical procedures in pilonidal sinus disease: A meta-analysis, merged data analysis, and comprehensive study on recurrence.
Synthesis in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 119 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Laser Hair Removal for Primary Treatment of Pilonidal Disease Requiring Surgical Intervention
Previously Operated Recurrent Pilonidal Sinus Treated With Crystallized Phenol: Twenty Years Experience
The Most Frequently Preferred Surgical Method In The Treatment Of Sacrococcygeal Pilonidal Disease; Multicenter Cohort Study
Randomized comparative clinical study between two treatment strategies in patients with pilonidal sinus: conventional care versus negative pressure therapy.
Who cites it
119 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- Negative pressure wound therapy in primary closure surgeries for pilonidal disease: a meta-analysis.Updates in surgery · 2026Pooled it
- The Use of Methylene Blue in Pilonidal Sinus Surgery Reduces the Risk of Recurrence: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- What is the Impact of Negative Pressure Wound Therapy on Healing in Patients Post Excision of Pilonidal Sinus? A Systematic Review and Meta-Analysis.International wound journal · 2025Pooled it
- Efficacy and safety of laser ablation for recurrent pilonidal sinus: a systematic review and meta‑analysis.International journal of colorectal disease · 2025Pooled it
- Midline and off-midline wound closure methods after surgical treatment for pilonidal sinus.The Cochrane database of systematic reviews · 2024Pooled it
- Non-excisional techniques for the treatment of intergluteal pilonidal sinus disease: a systematic review.Techniques in coloproctology · 2023Pooled it
- Laser treatment of pilonidal disease: a systematic review.Lasers in medical science · 2022Pooled it
- German National Guideline on the management of pilonidal disease: update 2020.Langenbeck's archives of surgery · 2021Guideline
- Karydakis procedure versus Limberg flap for treatment of pilonidal sinus: an updated meta-analysis of randomized controlled trials.International journal of colorectal disease · 2021Pooled it
- Global Gender Differences in Pilonidal Sinus Disease: A Random-Effects Meta-Analysis.World journal of surgery · 2020Pooled it
- Surgical procedures in the pilonidal sinus disease: a systematic review and network meta-analysis.Scientific reports · 2020Pooled it
- A comparison of flap reconstruction vs the laying open technique or excision and direct suture for pilonidal sinus disease: A meta-analysis of randomised studies.International wound journal · 2019Pooled it
- A systematic review of classification systems for pilonidal sinus.Techniques in coloproctology · 2019Pooled it
- Efficacy and safety of RD2 Ver.02, a whole blood clot therapy, coupled with a minimally invasive procedure in pilonidal sinus: a phase II study.Techniques in coloproctology · 2024Trial
- Conservative Sinusectomy vs. excision and primary off-midline closure for pilonidal disease: a randomized controlled trial.International journal of colorectal disease · 2020Trial
- Effectiveness of topical use of LietofixTechniques in coloproctology · 2019Trial
- Excision with primary midline closure compared with Limberg flap in the treatment of sacrococcygeal pilonidal disease: a randomised clinical trial.Annals of the Royal College of Surgeons of England · 2019Trial
- Effect of triclosan-coated sutures on surgical site infections in pilonidal disease: prospective randomized study.International journal of colorectal disease · 2018Trial
- Article
- Article
59 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We systematically searched available databases. We reviewed 6,143 studies published from 1833 to 2017. Reports in English, French, German, Italian, and Spanish were considered, as were publications in other languages if definitive treatment and recurrence at specific follow-up times were described in an English abstract. We assessed data in the manner of a meta-analysis of RCTs; further we assessed non-RCTs in the manner of a merged data analysis. In the RCT analysis including 11,730 patients, Limberg & Dufourmentel operations were associated with low recurrence of 0.6% (95%CI 0.3-0.9%) 12 months and 1.8% (95%CI 1.1-2.4%) respectively 24 months postoperatively. Analysing 89,583 patients from RCTs and non-RCTs, the Karydakis & Bascom approaches were associated with recurrence of only 0.2% (95%CI 0.1-0.3%) 12 months and 0.6% (95%CI 0.5-0.8%) 24 months postoperatively. Primary midline closure exhibited long-term recurrence up to 67.9% (95%CI 53.3-82.4%) 240 months post-surgery. For most procedures, only a few RCTs without long term follow up data exist, but substitute data from numerous non-RCTs are available. Recurrence in PSD is highly dependent on surgical procedure and by follow-up time; both must be considered when drawing conclusions regarding the efficacy of a procedure.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.