Evidence map›Paper›PMID 29449462›Full record

ReviewScience (New York, N.Y.)2018

Enantioselective C(sp

Tyler G Saint-Denis, Ru-Yi Zhu, Gang Chen, Qing-Feng Wu, Jin-Quan Yu

Abstract readReview
In one paragraph

Review in Science (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Direct enantioselective C(spNature chemistry · 2026
    Article
  9. Review
  10. Intermolecular Enantioselective Nickel-Catalyzed Arylation of Un-Activated C(spAngewandte Chemie (International ed. in English) · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Ligand-Controlled Alkylation-Heck-C(spJournal of the American Chemical Society · 2025
    Article
  15. Article
  16. BiVOChemical science · 2025
    Article
  17. Transition-Metal-Catalyzed C(spTopics in current chemistry (Cham) · 2025
    Review
  18. Article
  19. Article
  20. Emergent Mechanisms in Biocatalysis.ACS central science · 2025
    Review

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tyler G Saint-DenisThe Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.ORCID 0000-0002-9152-2415
Ru-Yi ZhuThe Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.ORCID 0000-0001-5908-2555
Gang ChenThe Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.ORCID 0000-0003-1683-7676
Qing-Feng WuThe Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.ORCID 0000-0003-2993-9882
Jin-Quan YuThe Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. yu200@scripps.edu.ORCID 0000-0003-3560-5774

Funding

Ligand-promoted Enantioselective C-H Activation ReactionsR01GM084019 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI YU, JIN-QUAN · 2008 to 2024
$9.5M
NIGMS NIH HHS R01 GM084019
6 · The paper itself

Abstract

Organic molecules are rich in carbon-hydrogen bonds; consequently, the transformation of C-H bonds to new functionalities (such as C-C, C-N, and C-O bonds) has garnered much attention by the synthetic chemistry community. The utility of C-H activation in organic synthesis, however, cannot be fully realized until chemists achieve stereocontrol in the modification of C-H bonds. This Review highlights recent efforts to enantioselectively functionalize C(sp

Identifiers

PMID29449462
PMCPMC5862070

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.