Evidence map›Paper›PMID 29449436›Full record

ArticleHaematologica2018

Mixed-species RNAseq analysis of human lymphoma cells adhering to mouse stromal cells identifies a core gene set that is also differentially expressed in the lymph node microenvironment of mantle cell lymphoma and chronic lymphocytic leukemia patients.

Gustav Arvidsson, Johan Henriksson, Birgitta Sander, Anthony P Wright

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gustav ArvidssonDepartment of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Sweden.
Johan HenrikssonDepartment of Biosciences and Nutrition, Karolinska Institutet, Sweden.
Birgitta SanderDepartment of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital, Sweden.
Anthony P WrightDepartment of Laboratory Medicine, Clinical Research Center, Karolinska Institutet Stockholm, Sweden anthony.wright@ki.se.
Karolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A subset of hematologic cancer patients is refractory to treatment or suffers relapse, due in part to minimal residual disease, whereby some cancer cells survive treatment. Cell-adhesion-mediated drug resistance is an important mechanism, whereby cancer cells receive survival signals

Indexed as

Gene Expression ProfilingSequence Analysis, RNAAnimalsCell AdhesionCell LineCell Line, TumorCell SurvivalCoculture TechniquesDrug ResistanceGene Expression Regulation, NeoplasticHumansLeukemia, Lymphocytic, Chronic, B-CellLymphomaLymphoma, Mantle-CellMiceParacrine Communication

Identifiers

PMID29449436
PMCPMC5865428
OpenAlexW2792188876

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.