Evidence map›Paper›PMID 29449359›Full record

ArticleCirculation research2018

Pannexin Channel Inhibition: An Evolving Target to Lower Blood Pressure?

Sabine Huke

Abstract readEditorialComment
In one paragraph

Article in Circulation research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pannexin1 channels-a potential therapeutic target in inflammation.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Sabine HukeFrom the Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham. hukes@uab.edu.

Funding

Cardiomyocyte-mediated mechanisms of ischemiaR01HL128563 · NHLBI · VANDERBILT UNIVERSITY · PI PRABHU, SUMANTH D · 2015 to 2018
$1.5M
Pannexin channels in cardiac arrhythmiasR01HL128044 · NHLBI · VANDERBILT UNIVERSITY · PI KNOLLMANN, BJORN C, ZHOU, LUFANG · 2015 to 2018
$1.5M
NHLBI NIH HHS R01 HL128044NHLBI NIH HHS R01 HL128563
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antihypertensive AgentsSpironolactoneAldosteroneBlood PressureMineralocorticoid Receptor AntagonistsAldosteroneAntihypertensive AgentsMineralocorticoid Receptor AntagonistsSpironolactonealdosteroneEditorialseplerenonespironolactone

Identifiers

PMID29449359
PMCPMC5821142

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.