Evidence map›Paper›PMID 29449313›Full record

ArticleJournal of lipid research2018

Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure.

Mikael Larsson, Christopher M Allan, Patrick J Heizer, Yiping Tu, Norma P Sandoval, Rachel S Jung, Rosemary L Walzem, Anne P Beigneux, Stephen G Young, Loren G Fong

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Metabolic Crosstalk between Liver and Brain: From Diseases to Mechanisms.International journal of molecular sciences · 2024
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mikael LarssonDepartments of Medicine University of California Los Angeles, Los Angeles, CA 90095. Electronic address: larsson.lom@gmail.com.
Christopher M AllanDepartments of Medicine University of California Los Angeles, Los Angeles, CA 90095.
Patrick J HeizerDepartments of Medicine University of California Los Angeles, Los Angeles, CA 90095.
Yiping TuDepartments of Medicine University of California Los Angeles, Los Angeles, CA 90095.
Norma P SandovalDepartments of Medicine University of California Los Angeles, Los Angeles, CA 90095.
Rachel S JungDepartments of Medicine University of California Los Angeles, Los Angeles, CA 90095.
Rosemary L WalzemDepartment of Poultry Science and Faculty of Nutrition, Texas A&M University, College Station, TX 77843.
Anne P BeigneuxDepartments of Medicine University of California Los Angeles, Los Angeles, CA 90095.
Stephen G YoungDepartments of Medicine University of California Los Angeles, Los Angeles, CA 90095; Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095. Electronic address: sgyoung@mednet.ucla.edu.
Loren G FongDepartments of Medicine University of California Los Angeles, Los Angeles, CA 90095. Electronic address: lfong@mednet.ucla.edu.
University of California, Los Angeles · USTexas A&M University · US

Funding

The Lipin Protein Family and Triglyceride Metabolism P01HL090553 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI YOUNG, STEPHEN G. · 2008 to 2018
$23.3M
Refining Physiologic Mechanisms for Intravascular Triglyceride MetabolismR01HL087228 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEIGNEUX, ANNE, FONG, LOREN GI · 2007 to 2024
$7.8M
Investigating Mechanisms for Lipid Transport in Health and DiseaseR35HL139725 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI YOUNG, STEPHEN G. · 2018 to 2024
$6.1M
Defining mechanisms for lipid transport across capillary endothelial cellsR01HL125335 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI YOUNG, STEPHEN G. · 2015 to 2017
$1.2M
NHLBI NIH HHS P01 HL090553NHLBI NIH HHS R01 HL087228NHLBI NIH HHS R01 HL125335NHLBI NIH HHS R35 HL139725
6 · The paper itself

Abstract

Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1), an endothelial cell protein, binds LPL in the subendothelial spaces and transports it to the capillary lumen. In

Indexed as

Cold TemperatureThermogenesisAnimalsApolipoproteins BMiceMice, KnockoutReceptors, LipoproteinTriglyceridesApolipoproteins BGPIHBP1 protein, humanReceptors, LipoproteinTriglyceridesglycosylphosphatidylinositol-anchored high density lipoprotein–binding protein 1lipoprotein lipasetriglyceride metabolism

Identifiers

PMID29449313
PMCPMC5880501
OpenAlexW2788993430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.