ArticleAJNR. American journal of neuroradiology2018
Modeling Early Postnatal Brain Growth and Development with CT: Changes in the Brain Radiodensity Histogram from Birth to 2 Years.
Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 9 citations in OpenAlex.
- Article
- Hounsfield unit and gray-white matter ratio estimates in pediatric normal controls used in studies evaluating head computed tomography.Neuroimage. Reports · 2026Article
- Automatic segmentation and quantitative analysis of brain CT volume in 2-year-olds using deep learning model.Frontiers in neurology · 2025Article
- Pitfalls in the interpretation of pediatric head CTs: what the emergency radiologist needs to know.Emergency radiology · 2022Review
- Zika virus vertical transmission in interferon receptor1-antagonized Rag1Acta neuropathologica communications · 2022Article
- Head CT: Toward Making Full Use of the Information the X-Rays Give.AJNR. American journal of neuroradiology · 2021Review
- The effects of the skull on CT imaging of the brain: a skull and brain phantom study.The British journal of radiology · 2021Article
- Pediatric Head CT: Automated Quantitative Analysis with Quantile Regression.AJNR. American journal of neuroradiology · 2021Article
- Aging and the Brain: A Quantitative Study of Clinical CT Images.AJNR. American journal of neuroradiology · 2020Article
- A Radiodensity Histogram Study of the Brain in Multiple Sclerosis.Tomography (Ann Arbor, Mich.) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe majority of brain growth and development occur in the first 2 years of life. This study investigated these changes by analysis of the brain radiodensity histogram of head CT scans from the clinical population, 0-2 years of age. MATERIALS AND
methodsOne hundred twenty consecutive head CTs with normal findings meeting the inclusion criteria from children from birth to 2 years were retrospectively identified from 3 different CT scan platforms. Histogram analysis was performed on brain-extracted images, and histogram mean, mode, full width at half maximum, skewness, kurtosis, and SD were correlated with subject age. The effects of scan platform were investigated. Normative curves were fitted by polynomial regression analysis.
resultsAverage total brain volume was 360 cm
conclusionsNormative metrics of the brain radiodensity histogram derived from routine clinical head CT images can be used to develop a model of normal brain development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.