Evidence map›Paper›PMID 29448996›Full record

ArticleJournal of chromatography. A2018

Automating data analysis for two-dimensional gas chromatography/time-of-flight mass spectrometry non-targeted analysis of comparative samples.

Ivan A Titaley, O Maduka Ogba, Leah Chibwe, Eunha Hoh, Paul H-Y Cheong, Staci L Massey Simonich

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of chromatography. A, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ivan A TitaleyDepartment of Chemistry, Oregon State University, Corvallis, OR, 97331, USA.
O Maduka OgbaDepartment of Chemistry, Oregon State University, Corvallis, OR, 97331, USA; Department of Chemistry, Pomona College, Claremont, CA, 91711, USA.
Leah ChibweDepartment of Chemistry, Oregon State University, Corvallis, OR, 97331, USA.
Eunha HohGraduate School of Public Health, San Diego State University, San Diego, CA, 92182, USA.
Paul H-Y CheongDepartment of Chemistry, Oregon State University, Corvallis, OR, 97331, USA. Electronic address: paulc@science.oregonstate.edu.
Staci L Massey SimonichDepartment of Chemistry, Oregon State University, Corvallis, OR, 97331, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 97331, USA. Electronic address: staci.simonich@oregonstate.edu.

Funding

Research Experience and Training Coordination CoreP42ES016465 · NIEHS · OREGON STATE UNIVERSITY · PI Robyn L Tanguay · 2009 to 2026
$52.5M
Reducing Susceptibility to Environmental Stress Throughout the Life SpanP30ES000210 · NIEHS · OREGON STATE UNIVERSITY · PI BECKMAN, JOSEPH S · 1985 to 2015
$21.4M
MODE OF ACTION OF ENVIRONMENTAL TOXICANTST32ES007060 · NIEHS · OREGON STATE UNIVERSITY · PI Jamie DeWitt, Siva Kumar Kolluri · 1985 to 2026
$11.6M
Sources and Sins of Halogenated Organic Compounds in the Marine EnvironmentP01ES021921 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MOORE, BRADLEY S · 2012 to 2016
$1.9M
NIEHS NIH HHS P01 ES021921NIEHS NIH HHS P30 ES000210NIEHS NIH HHS P42 ES016465NIEHS NIH HHS T32 ES007060
6 · The paper itself

Abstract

Non-targeted analysis of environmental samples, using comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GC × GC/ToF-MS), poses significant data analysis challenges due to the large number of possible analytes. Non-targeted data analysis of complex mixtures is prone to human bias and is laborious, particularly for comparative environmental samples such as contaminated soil pre- and post-bioremediation. To address this research bottleneck, we developed OCTpy, a Python™ script that acts as a data reduction filter to automate GC × GC/ToF-MS data analysis from LECO

Indexed as

Gas Chromatography-Mass SpectrometryBiodegradation, EnvironmentalEnvironmental MonitoringEnvironmental PollutantsPolycyclic Aromatic HydrocarbonsSoftwareSoilEnvironmental PollutantsPolycyclic Aromatic HydrocarbonsSoilGC × GC/ToF-MSLECO(®) ChromaTOF(®)Non-targeted analysisPython™Statistical compare

Identifiers

PMID29448996
PMCPMC5909067

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.