Evidence map›Paper›PMID 29447429›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2018

Arterial stiffness and subendocardial viability ratio in patients with peripheral arterial disease.

Giovanni Scandale, Gabriel Dimitrov, Martino Recchia, Gianni Carzaniga, Marzio Minola, Edoardo Perilli, Maria Carotta, Mariella Catalano

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Cardiovascular endpoints in relation to the central arterial pressure-time indexes.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  4. Article
  5. Article
  6. Observational
  7. Research Progress and Clinical Value of Subendocardial Viability Ratio.Journal of the American Heart Association · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Arterial Stiffness Assessed by Cardio-Ankle Vascular Index.International journal of molecular sciences · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Giovanni ScandaleResearch Center on Vascular Diseases and Angiology Unit, University of Milan, Milan, Italy.
Gabriel DimitrovResearch Center on Vascular Diseases and Angiology Unit, University of Milan, Milan, Italy.
Martino RecchiaMedistat sas Milan, Milan, Italy.
Gianni CarzanigaResearch Center on Vascular Diseases and Angiology Unit, University of Milan, Milan, Italy.ORCID 0000-0002-2374-2766
Marzio MinolaResearch Center on Vascular Diseases and Angiology Unit, University of Milan, Milan, Italy.
Edoardo PerilliResearch Center on Vascular Diseases and Angiology Unit, University of Milan, Milan, Italy.
Maria CarottaResearch Center on Vascular Diseases and Angiology Unit, University of Milan, Milan, Italy.
Mariella CatalanoResearch Center on Vascular Diseases and Angiology Unit, University of Milan, Milan, Italy.
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial stiffening is a hallmark of the aging process and atherosclerosis, including peripheral arterial disease (PAD). We investigated the associations between carotid-femoral pulse wave velocity (c-fPWV), augmentation index corrected for heart rate (Aix@HR75), ankle brachial index (ABI), and subendocardial viability ratio (SEVR), an indicator of cardiac perfusion. The c-fPWV, Aix@HR75, and SEVR was estimated using applanation tonometry. The ankle systolic pressure measurements for the calculation of the ABI were obtained using an 8-mHz Doppler probe. The study group included 555 subjects, mean age 63 ± 11 years (248 PAD (ABI < 1.0), and 307 non-PAD (ABI ≥ 1.0 ≤ 1.3). After the stepwise selection process in both PAD and non-PAD patients SEVR was not related to c-fPWV and ABI (P = .154; P = .156) and (P = .101; P = .402), respectively. In PAD patients, SEVR was negatively related to Aix@HR75 (P < .0001) and aortic PP (P = .0005). In conclusion, arterial stiffness is associated with non-invasive indices of myocardial perfusion in PAD patients, suggesting a potential pathophysiological link for increased cardiovascular events.

Indexed as

AgedAnkle Brachial IndexFemaleHumansHypertensionMaleMiddle AgedPeripheral Arterial DiseasePulse Wave AnalysisVascular Stiffnessarterial stiffnessperipheral arterial diseasesubendocardial viability

Identifiers

PMID29447429
PMCPMC8031258
OpenAlexW2791875058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.