Evidence map›Paper›PMID 29447345›Full record

ArticleBriefings in bioinformatics2019

The BioCyc collection of microbial genomes and metabolic pathways.

Peter D Karp, Richard Billington, Ron Caspi, Carol A Fulcher, Mario Latendresse, Anamika Kothari, Ingrid M Keseler, Markus Krummenacker, Peter E Midford, Quang Ong and 3 more

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 569 papers.

0numbers the graph read from it
0cells of the map it votes in
569citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

569 citing papers in PubMed.

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509 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peter D KarpSRI Bioinformatics Research Group (BRG).
Richard BillingtonSRI International.
Ron CaspiSRI International.
Carol A FulcherSRI International.
Mario LatendresseSRI International.
Anamika KothariSRI International.
Ingrid M KeselerSRI International.
Markus KrummenackerSRI International.
Peter E MidfordSRI International.
Quang OngSRI International.
Wai Kit OngSRI International.
Suzanne M PaleySRI International.
Pallavi SubhravetiSRI International.

Funding

The MetaCyc & BioCyc Pathway/Genome Databases (SRI Proposal ECU 14-630)R01GM080746 · NIGMS · SRI INTERNATIONAL · PI CASPI, RON, KARP, PETER D · 2007 to 2021
$15.6M
The EcoCyc Model Organism Database for Escherichia coli [SRI Proposal ECU 14-631]U24GM077678 · NIGMS · SRI INTERNATIONAL · PI KARP, PETER D · 2006 to 2018
$12.3M
Robust Software Components for Model Organism DatabasesR01GM075742 · NIGMS · SRI INTERNATIONAL · PI KARP, PETER D · 2005 to 2019
$12.0M
The EcoCyc Model Organism Database for Escherichia coliR01GM077678 · NIGMS · SRI INTERNATIONAL · PI KARP, PETER D · 2019 to 2022
$4.6M
NIGMS NIH HHS R01 GM075742NIGMS NIH HHS R01 GM077678NIGMS NIH HHS R01 GM080746NIGMS NIH HHS U24 GM077678
6 · The paper itself

Abstract

BioCyc.org is a microbial genome Web portal that combines thousands of genomes with additional information inferred by computer programs, imported from other databases and curated from the biomedical literature by biologist curators. BioCyc also provides an extensive range of query tools, visualization services and analysis software. Recent advances in BioCyc include an expansion in the content of BioCyc in terms of both the number of genomes and the types of information available for each genome; an expansion in the amount of curated content within BioCyc; and new developments in the BioCyc software tools including redesigned gene/protein pages and metabolite pages; new search tools; a new sequence-alignment tool; a new tool for visualizing groups of related metabolic pathways; and a facility called SmartTables, which enables biologists to perform analyses that previously would have required a programmer's assistance.

Indexed as

Genome, MicrobialMetabolic Networks and PathwaysSoftwareComputational BiologyDatabases, GeneticEscherichia coliGenomicsInternetModels, BiologicalSearch Enginegenome databasesmetabolic pathway databasesmicrobial genome databases

Identifiers

PMID29447345
PMCPMC6781571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.