ArticlePloS one2018
Comparison of viral infection in healthcare-associated pneumonia (HCAP) and community-acquired pneumonia (CAP).
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Detection of community-acquired respiratory viruses in allogeneic stem-cell transplant recipients and controls-A prospective cohort study.Transplant infectious disease : an official journal of the Transplantation Society · 2020Trial
- Impact of respiratory viruses detection on outcomes in ventilated nosocomial pneumonia: an exposed/unexposed study.Annals of intensive care · 2025Article
- Exploring the role of respiratory virus infections in aspiration pneumonia: a comprehensive analysis of cases with lower respiratory tract infections.BMC pulmonary medicine · 2025Article
- Clinical applications of artificial intelligence in identification and management of bacterial infection: Systematic review and meta-analysis.Saudi journal of biological sciences · 2024Review
- Clinical features and viral etiology of acute respiratory infection in an outpatient fever clinic during COVID-19 pandemic in a tertiary hospital in Nanjing, China.Journal of clinical laboratory analysis · 2022Article
- Epidemiologic Characteristics and Clinical Significance of Respiratory Viral Infections Among Adult Patients Admitted to the Intensive Care Unit.Frontiers in medicine · 2022Article
- Article
- Epidemiological and clinical characteristics of community-acquired and nosocomial influenza cases and risk factors associated with complications: A four season analysis of all adult patients admitted in a tertiary hospital.Influenza and other respiratory viruses · 2021Observational
- Update in Viral Infections in the Intensive Care Unit.Frontiers in medicine · 2021Review
- Significance of congestive heart failure as a cause of pleural effusion: Pilot data from a large multidisciplinary teaching hospital.Cardiology journal · 2020Article
- Disease Burden and Etiologic Distribution of Community-Acquired Pneumonia in Adults: Evolving Epidemiology in the Era of Pneumococcal Conjugate Vaccines.Infection & chemotherapy · 2018Review
- Pulmonary influenza A virus infection leads to suppression of the innate immune response to dermal injury.PLoS pathogens · 2018Article
- Spectrum of respiratory viral infections in liver disease patients with cirrhosis admitted in critical care unit.Journal of laboratory physiciansArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough viruses are known to be the second most common etiological factor in community-acquired pneumonia (CAP), the respiratory viral profile of the patients with healthcare-associated pneumonia (HCAP) has not yet been elucidated. We investigated the prevalence and the clinical impact of respiratory virus infection in adult patients with HCAP.
methodsPatients admitted with HCAP or CAP, between January and December 2016, to a tertiary referral hospital in Korea, were prospectively enrolled, and virus identification was performed using reverse-transcription polymerase chain reaction (RT-PCR).
resultsAmong 452 enrolled patients (224 with HCAP, 228 with CAP), samples for respiratory viruses were collected from sputum or endotracheal aspirate in 430 (95.1%) patients and from nasopharyngeal specimens in 22 (4.9%) patients. Eighty-seven (19.2%) patients had a viral infection, and the proportion of those with viral infection was significantly lower in the HCAP than in the CAP group (13.8% vs 24.6%, p = 0.004). In both the HCAP and CAP groups, influenza A was the most common respiratory virus, followed by entero-rhinovirus. The seasonal distributions of respiratory viruses were also similar in both groups. In the HCAP group, the viral infection resulted in a similar length of hospital stay and in-hospital mortality as viral-bacterial coinfection and bacterial infection, and the CAP group showed similar results.
conclusionsThe prevalence of viral infection in patients with HCAP was lower than that in patients with CAP, and resulted in a similar prognosis as viral-bacterial coinfection or bacterial infection.
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