Evidence map›Paper›PMID 29446224›Full record

ArticlePhysiological reports2018

Comparative effects of small intestinal glucose on blood pressure, heart rate, and noradrenaline responses in obese and healthy subjects.

Laurence G Trahair, Tongzhi Wu, Christine Feinle-Bisset, Chinmay S Marathe, Christopher K Rayner, Michael Horowitz, Karen L Jones

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Laurence G TrahairSchool of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Tongzhi WuSchool of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Christine Feinle-BissetSchool of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Chinmay S MaratheSchool of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Christopher K RaynerSchool of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Michael HorowitzSchool of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Karen L JonesSchool of Medicine, University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0002-1155-5816
National Health and Medical Research Council · AURoyal Adelaide Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meal consumption leads to an increase in sympathetic output to compensate for hemodynamic changes and maintain blood pressure (BP). Obesity is associated with a blunting of the sympathetic response to meal ingestion, but interpretation of studies investigating these responses is compromised by their failure to account for the rate of gastric emptying, which is an important determinant of postprandial cardiovascular and sympathetic responses and, in both health and obesity, exhibits a wide interindividual variation. We sought to determine the effects of intraduodenal glucose infusion, bypassing gastric emptying, on BP, heart rate (HR), and noradrenaline responses in obese and healthy control subjects. 12 obese subjects (age 36.6 ± 3.9 years, body mass index (BMI) 36.1 ± 1.3 kg/m

Indexed as

Blood PressureHeart RateAdultCase-Control StudiesFemaleGlucoseHumansIntestine, SmallMaleMiddle AgedNorepinephrineObesitySympathetic Nervous SystemGlucoseNorepinephrineGastric emptyingintraduodenalsympathetic

Identifiers

PMID29446224
PMCPMC5812881
OpenAlexW2792368710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.