Evidence map›Paper›PMID 29445984›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2018

Impact of antibiotic prophylaxis on catheter-associated urinary tract infections during atrial fibrillation ablation.

David E Lewandowski, David Pierce, Anne Barnett, Emmanuel Sampene, Nasia Safdar, Michael E Field, Jennifer M Wright

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

David E LewandowskiUniversity of Wisconsin Hospitals and Clinics, 600 Highland Ave, Madison, WI, 53792, USA. david.e.lewandowski@gmail.com.ORCID http://orcid.org/0000-0001-9489-6423
David PierceUniversity of Wisconsin Hospitals and Clinics, 600 Highland Ave, Madison, WI, 53792, USA.
Anne BarnettUniversity of Wisconsin Hospitals and Clinics, 600 Highland Ave, Madison, WI, 53792, USA.
Emmanuel SampeneUniversity of Wisconsin Hospitals and Clinics, 600 Highland Ave, Madison, WI, 53792, USA.
Nasia SafdarUniversity of Wisconsin Hospitals and Clinics, 600 Highland Ave, Madison, WI, 53792, USA.
Michael E FieldUniversity of Wisconsin Hospitals and Clinics, 600 Highland Ave, Madison, WI, 53792, USA.
Jennifer M WrightUniversity of Wisconsin Hospitals and Clinics, 600 Highland Ave, Madison, WI, 53792, USA.
UW Health University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUrinary catheter placement is common during atrial fibrillation (AF) ablation when performed under general anesthesia. Whether patients undergoing AF ablation would benefit from prophylactic antibiotics is unknown.

methodsPatients undergoing AF ablation in a single center from December 2011 until June 2016 were included. All patients received urinary catheters and general anesthesia. After June 2014, patients received antibiotic prophylaxis with a single dose of oral nitrofurantoin and a catheter insertion checklist performed prior to urinary catheter placement. The intervention group (group B) was compared to the pre-intervention group (group A) for development of the primary outcome. A multivariable logistic regression was performed to determine if any of the covariates were associated with catheter-associated urinary tract infection (CAUTI) development.

resultsThere were 452 patients who underwent AF ablation during the analysis period (212 in group A and 240 in group B). The average patient age was 60 years (range 23-85) and 70% of the patients were male. Utilizing an intention to treat approach, there was a significantly lower incidence of CAUTI in the intervention group compared to controls (4.7 vs. 0.83%; OR 0.18, p = 0.029). There were no significant differences between the groups with respect to urinary tract infection risk factors or catheter duration.

conclusionAn intervention consisting of a single dose of nitrofurantoin in addition to performance of a catheter insertion checklist prior to urinary catheter insertion decreased CAUTI by 80% in patients undergoing AF ablation. Such interventions may be beneficial to reduce CAUTI in this group of patients.

Indexed as

AgedAntibiotic ProphylaxisAtrial FibrillationCatheter AblationCatheter-Related InfectionsCohort StudiesFemaleFollow-Up StudiesHospitals, UniversityHumansIncidenceMaleMiddle AgedPreoperative CareReference ValuesRetrospective StudiesAntibiotic prophylaxisAtrial fibrillationCatheter ablationQuality improvementUrinary catheter-associated urinary tract infection

Identifiers

PMID29445984
OpenAlexW2789866935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.