ReviewCurrent atherosclerosis reports2018
Gender Differences in Epidemiology, Pathophysiology, and Treatment of Hypertension.
Review in Current atherosclerosis reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.
- Pooled it
- Clustering metabolic and behavioral risk factors for hypertension: evidence from a longitudinal cohort in western Iran.Scientific reports · 2026Article
- Article
- Article
- Association between polypharmacy and hypertension in the Iranian population aged 50 years or older: Iranian Multicenter Osteoporosis Study (IMOS-2021).BMC primary care · 2025Article
- A comprehensive narrative review on precision medicine approach to hypertension: exploring the role of genetics, epigenetics, microbiome, and artificial intelligence.Journal of health, population, and nutrition · 2025Review
- Article
- Hypertension in a low-income, predominantly afrocolombian city: Prevalence, awareness, treatment, control, and risk factors from a community-based screeningBiomedica : revista del Instituto Nacional de Salud · 2025Article
- Effects of Menstrual Cycle on Exercise Treadmill Parameters and Cardiac Troponin Release in Premenstrual Women.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Global burden and trends of hypertension-related chronic kidney disease attributable to high body mass index or low physical activity: an analysis based on global burden of disease study 2021 data.Frontiers in nutrition · 2025Article
- The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.Frontiers in cardiovascular medicine · 2025Article
- Prevalence and risk factors of hypertension among clients seeking care at Selected Healthcare Facilities in Kenya.PloS one · 2025Article
- Analysis of Blood Pressure Status and Influencing Factors Among 7218 Emergency Department Nurses: An Observational Cross-Sectional Study.International journal of hypertension · 2025Article
- Global burden and trends of high BMI-attributable chronic kidney disease: a comprehensive analysis from 1990 to 2021 and projections to 2035.Frontiers in nutrition · 2025Article
- Have People Treated With Antihypertensives Been Diagnosed With Hypertension? A Cross-Sectional Study in Stockholm, Sweden.Pharmacoepidemiology and drug safety · 2025Article
- The Pathophysiology, Prognosis and Treatment of Hypertension in Females from Pregnancy to Post-menopause: A Review.Current heart failure reports · 2024Review
- Sex differences in CKD risk factors across ethnic groups.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Article
- Sarcopenia severity is related to arterial stiffness and hypertension in older Korean population without underweight and obesity: population based cross-sectional study.Frontiers in public health · 2024Article
- High-resolution magnetic resonance imaging investigation of the connection between the triglyceride-glucose index and intracranial arterial remodeling: a retrospective cross-sectional study.Quantitative imaging in medicine and surgery · 2023Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThis review aims to examine gender differences in both the epidemiology and pathophysiology of hypertension and to explore gender peculiarities on the effects of antihypertensive agents in decreasing BP and CV events. RECENT
findingsMen and women differ in prevalence, awareness, and control rate of hypertension in an age-dependent manner. Studies suggest that sex hormones changes play a pivotal role in the pathophysiology of hypertension in postmenopausal women. Estrogens influence the vascular system inducing vasodilatation, inhibiting vascular remodeling processes, and modulating the renin-angiotensin aldosterone system and the sympathetic system. This leads to a protective effect on arterial stiffness during reproductive age that is dramatically reversed after menopause. Data on the efficacy of antihypertensive therapy between genders are conflicting, and the underrepresentation of aged women in large clinical trials could influence the results. Therefore, further clinical research is needed to uncover potential gender differences in hypertension to promote the development of a gender-oriented approach to antihypertensive treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.