Evidence map›Paper›PMID 29445741›Full record

ArticleBioMed research international2017

PSBinder: A Web Service for Predicting Polystyrene Surface-Binding Peptides.

Ning Li, Juanjuan Kang, Lixu Jiang, Bifang He, Hao Lin, Jian Huang

Abstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Validation ofACS central science · 2026
    Article
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  3. Article
  4. Article
  5. Article
  6. Review
  7. In Silico Design and Analysis of Plastic-Binding Peptides.The journal of physical chemistry. B · 2023
    Article
  8. Modular Design for Proteins Assembling into Antifouling Coatings: Case of Gold Surfaces.Langmuir : the ACS journal of surfaces and colloids · 2023
    Article
  9. Article
  10. CSM-peptides: A computational approach to rapid identification of therapeutic peptides.Protein science : a publication of the Protein Society · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Anticancer Peptide PredictionFrontiers in genetics · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ning LiCenter for Informational Biology, University of Electronic Science and Technology of China, Sichuan, China.
Juanjuan KangCenter for Informational Biology, University of Electronic Science and Technology of China, Sichuan, China.
Lixu JiangCenter for Informational Biology, University of Electronic Science and Technology of China, Sichuan, China.
Bifang HeCenter for Informational Biology, University of Electronic Science and Technology of China, Sichuan, China.ORCID 0000-0003-3420-9905
Hao LinCenter for Informational Biology, University of Electronic Science and Technology of China, Sichuan, China.
Jian HuangCenter for Informational Biology, University of Electronic Science and Technology of China, Sichuan, China.ORCID 0000-0003-3282-8892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polystyrene surface-binding peptides (PSBPs) are useful as affinity tags to build a highly effective ELISA system. However, they are also a quite common type of target-unrelated peptides (TUPs) in the panning of phage-displayed random peptide library. As TUP, PSBP will mislead the analysis of panning results if not identified. Therefore, it is necessary to find a way to quickly and easily foretell if a peptide is likely to be a PSBP or not. In this paper, we describe PSBinder, a predictor based on SVM. To our knowledge, it is the first web server for predicting PSBP. The SVM model was built with the feature of optimized dipeptide composition and 87.02% (MCC = 0.74; AUC = 0.91) of peptides were correctly classified by fivefold cross-validation. PSBinder can be used to exclude highly possible PSBP from biopanning results or to find novel candidates for polystyrene affinity tags. Either way, it is valuable for biotechnology community.

Indexed as

SoftwareAmino Acid SequenceBiophysical PhenomenaInternetPeptidesPolystyrenesProtein BindingSignal TransductionSurface PropertiesPeptidesPolystyrenes

Identifiers

PMID29445741
PMCPMC5763211

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.