Evidence map›Paper›PMID 29445734›Full record

ArticleBioMed research international2017

Failure of the PTEN/aPKC/Lgl Axis Primes Formation of Adult Brain Tumours in

Simona Paglia, Manuela Sollazzo, Simone Di Giacomo, Dario de Biase, Annalisa Pession, Daniela Grifoni

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Frontiers in cell and developmental biology · 2026
    Review
  2. Article
  3. Article
  4. Cells · 2021
    Review
  5. Frontiers in genetics · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Simona PagliaDepartment of "Pharmacy and Biotechnology", University of Bologna, Via Selmi 3, 40126 Bologna, Italy.
Manuela SollazzoDepartment of "Pharmacy and Biotechnology", University of Bologna, Via Selmi 3, 40126 Bologna, Italy.
Simone Di GiacomoDepartment of "Pharmacy and Biotechnology", University of Bologna, Via Selmi 3, 40126 Bologna, Italy.
Dario de BiaseDepartment of "Pharmacy and Biotechnology", University of Bologna, Via Selmi 3, 40126 Bologna, Italy.ORCID 0000-0002-0609-8817
Annalisa PessionDepartment of "Pharmacy and Biotechnology", University of Bologna, Via Selmi 3, 40126 Bologna, Italy.
Daniela GrifoniDepartment of "Pharmacy and Biotechnology", University of Bologna, Via Selmi 3, 40126 Bologna, Italy.ORCID 0000-0001-7429-4062
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different regions in the mammalian adult brain contain immature precursors, reinforcing the concept that brain cancers, such as glioblastoma multiforme (GBM), may originate from cells endowed with stem-like properties. Alterations of the tumour suppressor gene

Indexed as

AnimalsBrain NeoplasmsCarcinogenesisCell DifferentiationCell PolarityDisease Models, AnimalDrosophila melanogasterDrosophila ProteinsGlioblastomaHumansNeural Stem CellsNeurogenesisProtein Kinase CPTEN PhosphohydrolaseSignal TransductionTumor Suppressor ProteinsDrosophila Proteinsl(2)gl protein, DrosophilaPKC-3 proteinProtein Kinase CPTEN PhosphohydrolasePTEN protein, DrosophilaTumor Suppressor Proteins

Identifiers

PMID29445734
PMCPMC5763105
OpenAlexW2776019109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.