Evidence map›Paper›PMID 29445490›Full record

ArticleClinical case reports2018

Primary growth hormone insensitivity and psychomotor delay.

Inma Castilla-Cortazar, Julieta Rodríguez De Ita, Gabriel A Aguirre, Joel Rodríguez-Rivera, Mariano García-Magariño, Irene Martín-Estal, Óscar Flores-Caloca, Carlos Diaz-Olachea

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Inma Castilla-CortazarEscuela de Medicina Tecnologico de Monterrey Monterrey Mexico.ORCID 0000-0002-2230-5927
Julieta Rodríguez De ItaEscuela de Medicina Tecnologico de Monterrey Monterrey Mexico.
Gabriel A AguirreEscuela de Medicina Tecnologico de Monterrey Monterrey Mexico.
Joel Rodríguez-RiveraEscuela de Medicina Tecnologico de Monterrey Monterrey Mexico.
Mariano García-MagariñoEscuela de Medicina Tecnologico de Monterrey Monterrey Mexico.
Irene Martín-EstalEscuela de Medicina Tecnologico de Monterrey Monterrey Mexico.
Óscar Flores-CalocaEscuela de Medicina Tecnologico de Monterrey Monterrey Mexico.
Carlos Diaz-OlacheaEscuela de Medicina Tecnologico de Monterrey Monterrey Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of short stature irresponsive to growth hormone (GH) replacement therapy. Low GH response to provocative tests and undetectable IGF-1 levels had suggested GH deficiency, while response to therapy indicated GH insensitivity. Molecular evaluation of the GH/IGF-1 axis should be performed in these cases to improve diagnosis and therapy.

Indexed as

GH/IGF‐1 axisGH insensitivityGH resistanceIGF‐1Laron Syndrome

Identifiers

PMID29445490
PMCPMC5799629

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.