ArticleJournal of vascular and interventional neurology2017
Investigation of Gender Differences and Exclusive Criteria in a Diabetic Acute Ischemic Stroke Population Treated with Recombinant Tissue-Type Plasminogen Activator (rtPA).
Article in Journal of vascular and interventional neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed.
- Age Stratification and Stroke Severity in the Telestroke Network.Journal of clinical medicine · 2023Article
- Stroke Severity among Men and Women Acute Ischemic Stroke Patients in the Telestroke Network.Cerebrovascular diseases extra · 2022Article
- Cholesterol reducer and thrombolytic therapy in acute ischemic stroke patients.Lipids in health and disease · 2020Article
- Gender and thrombolysis therapy in acute ischemic stroke patients with incidence of obesity.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Article
- The telestroke and thrombolysis therapy in diabetic stroke patients.Diabetology & metabolic syndrome · 2019Article
- Predictors of thrombolysis in the telestroke and non telestroke settings for hypertensive acute ischemic stroke patients.BMC neurology · 2018Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany studies have reported that women who survive stroke have less favorable outcomes than men in the use of rtPA, while others reported worse outcomes in men than women. The gender difference in the exclusion criteria in a diabetic stroke population is not fully understood. This issue was investigated in this study.
methodIn a diabetic stroke population from a stroke registry of data collected between January 2010 to June 30, 2016, the gender difference was determined using demographics and clinical factors. Comparison was determined using univariate analysis while multivariable model was used to adjust for the effect of confounding variables.
resultsIn a diabetic stroke population of 439 patients, more females were excluded than males (
conclusionIn a stroke population, women have a worse outcome than men in an untreated acute ischemic stroke population, but when treated there is no significant difference, suggesting a better treatment outcome for women compared to men. In a diabetic stroke population, the clinical variables for the exclusion criteria for women and men are significantly different, even after adjustment for confounding variables.
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Identifiers
29445435PMC5805905What OpenQuestion holds
Registered trials
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