Evidence map›Paper›PMID 29445400›Full record

ArticleInternational journal of rheumatology2017

Effect of

C Singgih Wahono, Cameleia Diah Setyorini, Handono Kalim, Nurdiana Nurdiana, Kusworini Handono

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of rheumatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05430087 phase2completednot on this mapstarted 2020, after this paper: background citation

The Combination of Vitamin D and Curcumin Piperine Attenuates the Disease Activity and Pro-Inflammatory Cytokines Levels in Systemic Lupus Erythematosus Patients

TypeinterventionalSponsorSaiful Anwar HospitalRan2020 to 2022Enrolled45ConditionsSystemic Lupus ErythematosusArmsObserve the clinical outcome and inflammatory cytokines levels in patients with systemic lupus erythematosus (SLE) after being supplemented with Cholecalciferol (Vitamin D3) and Curcumin-Piperine.
NCT07149961 nacompletednot on this mapstarted 2025, after this paper: background citation

Supplementation of Piperine and Curcumin (Curcuma Xanthorrhiza) Extract in ST Elevation Myocardial Infarction - SPICE STEMI Trial

TypeinterventionalSponsorUniversitas DiponegoroRan2025 to 2025Enrolled50ConditionsST Elevation Myocardial Infarction (STEMI), Malondialdehyde, Hs-CRP, CurcuminArmsCurcumin plus Piperine, Placebo capsules
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Diet and Systemic Lupus Erythematosus (SLE): From Supplementation to Intervention.International journal of environmental research and public health · 2022
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Review
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  14. Article
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  16. Article
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  20. Immunomodulatory Effects and Mechanisms ofFrontiers in pharmacology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

C Singgih WahonoRheumatology and Immunology Division, Department of Internal Medicine, Faculty of Medicine, Brawijaya University and Saiful Anwar General Hospital, Malang, Indonesia.
Cameleia Diah SetyoriniDepartment of Internal Medicine, Faculty of Medicine, Brawijaya University and Saiful Anwar Hospital, Malang, Indonesia.ORCID 0000-0002-3323-2911
Handono KalimRheumatology and Immunology Division, Department of Internal Medicine, Faculty of Medicine, Brawijaya University and Saiful Anwar General Hospital, Malang, Indonesia.ORCID 0000-0002-3827-5275
Nurdiana NurdianaPharmacology Department, Faculty of Medicine, Brawijaya University, Malang, Indonesia.
Kusworini HandonoClinical Pathology Department, Faculty of Medicine, Brawijaya University, Saiful Anwar General Hospital, Malang, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurcumin contained in

objectiveTo determine the effect of

methodsThis was a double-blind RCT conducted in Saiful Anwar Hospital, Malang, in January 2016-March 2017. Subjects were SLE active (SLEDAI > 3) with levels of 25(OH)D3 ≤ 30 ng/ml and divided into two groups: those receiving cholecalciferol 3 × 400 IU and placebo 3 × 1 tablets (group I) and those receiving 3 × 400 IU cholecalciferol and

resultsThere were no significant differences in SLEDAI reduction, decreased serum levels of IL-6, and increased levels of TGF-

Identifiers

PMID29445400
PMCPMC5763117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.