Evidence map›Paper›PMID 29445300›Full record

ReviewCancer management and research2018

Gastric cancer: epidemiology, prevention, classification, and treatment.

Robert Sitarz, Małgorzata Skierucha, Jerzy Mielko, G Johan A Offerhaus, Ryszard Maciejewski, Wojciech P Polkowski

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07126561 (Phase II Open Label Trial of Trastuzumab Deruxtecan), which is not on this map. Cited by 557 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
557citing papers in PubMed, 6 pooled it
95.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07126561 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Phase II Open Label Trial of Trastuzumab Deruxtecan (Enhertu, DS-8210) in HER2 Positive Newly Diagnosed Metastatic Esophageal, Gastric, GEJ Cancer Patients With an ECOG Performance Status of 2

TypeinterventionalSponsorUniversity of ChicagoRan2026 to 2028Enrolled43ConditionsHER2 Positive Newly Diagnosed Metastatic Esophageal, Gastric, GEJ Cancer Patients With an ECOG Performance Status of 2ArmsTrastuzumab Deruxtecan
3 · Its place in the literature

Who cites it

557 citing papers in PubMed, 6 syntheses or guidelines pooled it, 1,048 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Prevalence of Gastric Precursor Lesions in Countries With Differential Gastric Cancer Burden: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. International journal of molecular medicine · 2026
    Review
  16. Association ofTranslational cancer research · 2026
    Article
  17. Review
  18. Article
  19. Article
  20. Review

497 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Robert SitarzDepartment of Surgical Oncology, Medical University of Lublin, Lublin, Poland.
Małgorzata SkieruchaDepartment of Surgical Oncology, Medical University of Lublin, Lublin, Poland.
Jerzy MielkoDepartment of Surgical Oncology, Medical University of Lublin, Lublin, Poland.
G Johan A OfferhausDepartment of Pathology, University Medical Centre, Utrecht, The Netherlands.
Ryszard MaciejewskiDepartment of Human Anatomy, Medical University of Lublin, Lublin, Poland.
Wojciech P PolkowskiDepartment of Surgical Oncology, Medical University of Lublin, Lublin, Poland.
Medical University of Lublin · PLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is the second most common cause of cancer-related deaths in the world, the epidemiology of which has changed within last decades. A trend of steady decline in gastric cancer incidence rates is the effect of the increased standards of hygiene, conscious nutrition, and

Indexed as

classificationepidemiologygastric cancerrisk factorstreatment

Identifiers

PMID29445300
PMCPMC5808709
OpenAlexW2792603544

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.