ArticleNeuropsychiatric disease and treatment2018
The differences between patients with panic disorder and healthy controls in psychophysiological stress profile.
Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The Relations Between Sensory Modulation, Hyper Arousability and Psychopathology in Adolescents with Anxiety Disorders.Children (Basel, Switzerland) · 2025Article
- Deep learning-based stress detection from RR intervals in major depressive disorder, panic disorder, and healthy individuals.Frontiers in psychiatry · 2025Article
- Smaller hypothalamic subregion with paraventricular nucleus in patients with panic disorder.Brain imaging and behavior · 2024Article
- Automated classification of stress and relaxation responses in major depressive disorder, panic disorder, and healthy participants via heart rate variability.Frontiers in psychiatry · 2024Article
- A critical period for experience-dependent development of the feelings of safety during early infancy: A polyvagal perspective on anger and psychometric tools to assess perceived safety.Frontiers in integrative neuroscience · 2022Article
- Psychophysiological Markers of Fear and Anxiety.Current psychiatry reports · 2019Review
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Authors and funding
6 authors.
Funding
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Abstract
backgroundAlarming somatic symptoms, in particular, cardiovascular symptoms, are the characteristic feature of panic attacks. Increased cardiac mortality and morbidity have been found in these patients. Power spectral analysis of electrocardiogram R-R intervals is known to be a particularly successful tool in the detection of autonomic instabilities in various clinical disorders. Our study aimed to compare patients with panic disorder and healthy controls in heart rate variation (HRV) parameters (very-low-frequency [VLF], low-frequency [LF], and high-frequency [HF] band components of R-R interval) in baseline and during the response to the mental task. SUBJECTS AND
methodsWe assessed psychophysiological variables in 33 patients with panic disorder (10 men, 23 women; mean age 35.9±10.7 years) and 33 age- and gender-matched healthy controls (10 men, 23 women; mean age 35.8±12.1 years). Patients were treatment naïve. Heart rate, blood pressure, muscle tension, and HRV in basal conditions and after the psychological task were assessed. Power spectrum was computed for VLF (0.003-0.04 Hz), LF (0.04-0.15 Hz), and HF (0.15-0.40 Hz) bands using fast Fourier transformation.
resultsIn the baseline period, the VLF band was significantly lower in panic disorder group compared to controls (
conclusionThese findings revealed that patients suffering from panic disorder were characterized by relative sympathetic dominance (reactivity) in response to mental stress compared with healthy controls.
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