Evidence map›Paper›PMID 29445270›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2018

Alterations of the default mode network and cognitive impairments in patients with chronic obstructive pulmonary disease.

Xianwei Hu, Haibao Wang, Youhui Tu, Mengdi Fei, Minmin Yin, Guanghe Fei, Yongqiang Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
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  6. Article
  7. Article
  8. Article
  9. Effective Connectivity and Clinical Correlates in Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2026
    Article
  10. Review
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  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Moderate-to-Severe Obstructive Sleep Apnea and Cognitive Function Impairment in Patients with COPD.International journal of chronic obstructive pulmonary disease · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xianwei HuPulmonary Department, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Haibao WangRadiology Department, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Youhui TuPulmonary Department, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Mengdi FeiLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.
Minmin YinRadiology Department, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Guanghe FeiPulmonary Department, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Yongqiang YuRadiology Department, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: Cognitive impairment is a common extrapulmonary comorbidity in COPD patients. The default mode network (DMN) plays a critical role in maintaining the normal activities of humans, and its function can be evaluated by resting state functional magnetic resonance imaging. The aim of this study was to investigate the correlations between cognition and function changes of the DMN in COPD patients. Methods: One hundred and thirteen eligible participants including 30 control subjects and 83 COPD patients matched for demographic characteristics were recruited. All participants performed cognitive function tests and underwent resting state functional magnetic resonance imaging. Results: The total cognitive function scores of COPD patients were significantly different from those of control subjects ( Conclusion: COPD patients have cognitive impairments that correlate well with disease severity. FC changes in activated brain regions in the DMN may predict cognitive impairment, and the left posterior cingulate cortex and left hippocampus may be important brain regions related to cognitive impairment in COPD patients.

Indexed as

CognitionAgedBrainBrain MappingCase-Control StudiesCognition DisordersCross-Sectional StudiesFemaleHumansLungMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsPulmonary Disease, Chronic ObstructiveRisk Factorschronic obstructive pulmonary diseasecognitive functiondefault mode networkresting state functional magnetic resonance imaging

Identifiers

PMID29445270
PMCPMC5808710

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.