Evidence map›Paper›PMID 29445226›Full record

ArticleScientific reports2018

GCY-35/GCY-36-TAX-2/TAX-4 Signalling in O

Yuan-Hua Chen, Chang-Li Ge, Hong Wang, Ming-Hai Ge, Qing-Qin He, Yu Zhang, Wei Tian, Zheng-Xing Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Serotonin-Mediated Avoidance and Immune Suppression inBiochemistry research international · 2025
    Article
  2. Review
  3. Article
  4. Chemical-Genetic Interactions as a Means to Characterize Drug Synergy.Methods in molecular biology (Clifton, N.J.) · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yuan-Hua ChenKey Laboratory of Molecular Biophysics, Ministry of Education, and Department of Biophysics and Molecular Physiology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, P.R. China.
Chang-Li GeKey Laboratory of Molecular Biophysics, Ministry of Education, and Department of Biophysics and Molecular Physiology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, P.R. China.
Hong WangKey Laboratory of Molecular Biophysics, Ministry of Education, and Department of Biophysics and Molecular Physiology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, P.R. China.
Ming-Hai GeKey Laboratory of Molecular Biophysics, Ministry of Education, and Department of Biophysics and Molecular Physiology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, P.R. China.
Qing-Qin HeKey Laboratory of Molecular Biophysics, Ministry of Education, and Department of Biophysics and Molecular Physiology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, P.R. China.
Yu ZhangKey Laboratory of Molecular Biophysics, Ministry of Education, and Department of Biophysics and Molecular Physiology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, P.R. China.
Wei TianKey Laboratory of Molecular Biophysics, Ministry of Education, and Department of Biophysics and Molecular Physiology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, P.R. China.
Zheng-Xing WuKey Laboratory of Molecular Biophysics, Ministry of Education, and Department of Biophysics and Molecular Physiology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, P.R. China. ibbwuzx@mail.hust.edu.cn.
Huazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ethanol is a widely used beverage and abused drug. Alcoholism causes severe damage to human health and creates serious social problems. Understanding the mechanisms underlying ethanol actions is important for the development of effective therapies. Alcohol has a wide spectrum of effects on physiological activities and behaviours, from sensitization to sedation and even intoxication with increasing concentrations. Animals develop tolerance to ethanol. However, the underlying mechanisms are not well understood. In Caenorhabditis elegans, NPR-1 negatively regulates the development of acute tolerance to ethanol. Here, using in vivo Ca

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCyclic GMPDrug ToleranceEthanolGuanylate CyclaseGuanylate Cyclase-Activating ProteinsIon ChannelsOxygenReceptors, Neuropeptide YSensory Receptor CellsSignal TransductionCaenorhabditis elegans ProteinsCyclic GMPEthanolGCY-35 protein, C elegansGCY-36 protein, C elegansGuanylate CyclaseGuanylate Cyclase-Activating ProteinsIon ChannelsNPR-1 protein, C elegansOxygenReceptors, Neuropeptide Ytax-2 protein, C eleganstax-4 protein, C elegans

Identifiers

PMID29445226
PMCPMC5813177
OpenAlexW2805130894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.