Evidence map›Paper›PMID 29445199›Full record

ArticleScientific reports2018

Lack of T-bet reduces monocytic interleukin-12 formation and accelerates thrombus resolution in deep vein thrombosis.

Tanja Schönfelder, Moritz Brandt, Sabine Kossmann, Tanja Knopp, Thomas Münzel, Ulrich Walter, Susanne H Karbach, Philip Wenzel

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Immune cell-mediated venous thrombus resolution.Research and practice in thrombosis and haemostasis · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. The role of monocytes in thrombotic diseases: a review.Frontiers in cardiovascular medicine · 2023
    Review
  10. Review
  11. Article
  12. The role of bone marrow-derived cells in venous thromboembolism.The international journal of biochemistry & cell biology · 2020
    Review
  13. Insights from experimental post-thrombotic syndrome and potential for novel therapies.Translational research : the journal of laboratory and clinical medicine · 2020
    Review
  14. Resolution of Deep Venous Thrombosis: Proposed Immune Paradigms.International journal of molecular sciences · 2020
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tanja SchönfelderCenter for Thrombosis and Hemostasis Mainz, Mainz, Germany.
Moritz BrandtCenter for Thrombosis and Hemostasis Mainz, Mainz, Germany.
Sabine KossmannCenter for Thrombosis and Hemostasis Mainz, Mainz, Germany.
Tanja KnoppCenter for Thrombosis and Hemostasis Mainz, Mainz, Germany.
Thomas MünzelCenter for Thrombosis and Hemostasis Mainz, Mainz, Germany.
Ulrich WalterCenter for Thrombosis and Hemostasis Mainz, Mainz, Germany.
Susanne H KarbachCenter for Thrombosis and Hemostasis Mainz, Mainz, Germany.
Philip WenzelCenter for Thrombosis and Hemostasis Mainz, Mainz, Germany. wenzelp@uni-mainz.de.
Johannes Gutenberg University Mainz · DEUniversity Medical Center of the Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of leukocytes in deep vein thrombosis (DVT) resolution is incompletely understood. We determined how depletion of lysozyme positive (LysM

Indexed as

AnimalsAntigens, LyDiphtheria ToxinDisease Models, AnimalHumansInterleukin-12 Subunit p40MaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicMonocytesNeovascularization, PhysiologicT-bet Transcription FactorT-Box Domain ProteinsTransplantation ChimeraAntigens, LyDiphtheria ToxinInterleukin-12 Subunit p40Ly-6C antigen, mouseT-bet Transcription FactorT-Box Domain ProteinsVascular Endothelial Growth Factor A

Identifiers

PMID29445199
PMCPMC5813037
OpenAlexW2805921025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.