ArticleScientific reports2018
Differences in frontotemporal dysfunction during social and non-social cognition tasks between patients with autism spectrum disorder and schizophrenia.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Cortical Region Reporting Patterns in Neurodevelopmental Disorders: A Systematic Review of fNIRS Studies.Biosensors · 2026Pooled it
- Autism spectrum disorder and schizophrenia: An updated conceptual review.Autism research : official journal of the International Society for Autism Research · 2022Pooled it
- A systematic review of studies that used NIRS to measure neural activation during emotion processing in healthy individuals.Social cognitive and affective neuroscience · 2021Pooled it
- Physiological adjustment effects of viewing natural environment images on heart rate variability in individuals with depressive and anxiety disorders.Scientific reports · 2025Trial
- The Mood-Improving Effect of Viewing Images of Nature and Its Neural Substrate.International journal of environmental research and public health · 2021Trial
- Functional Near-Infrared Spectroscopy in Schizophrenia Research: Progress, Challenges, and Future Directions.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- The functional near infrared spectroscopy applications in children with developmental diseases: a review.Frontiers in neurology · 2025Review
- The promising fNIRS: Uncovering the function of prefrontal working memory networks based on multi-cognitive tasks.Frontiers in psychiatry · 2022Article
- Prefrontal activity during the emotional go/no-go task and computational markers of risk-based decision-making predict future relapse in alcohol use disorder.Frontiers in psychiatry · 2022Article
- fNIRS-derived neurocognitive ratio as a biomarker for neuropsychiatric diseases.Neurophotonics · 2021Article
- Reduced Brain Activation in Response to Social Cognition Tasks in Autism Spectrum Disorder with and without Depression.Neuropsychiatric disease and treatment · 2021Article
- Ventrolateral prefrontal hemodynamic responses in autism spectrum disorder with and without depression.PloS one · 2021Article
- Social Cognition in a Research Domain Criteria Perspective: A Bridge Between Schizophrenia and Autism Spectra Disorders.Frontiers in psychiatry · 2020Review
- Social Cognition in Schizophrenia and Autism Spectrum Disorders: A Systematic Review and Meta-Analysis of Direct Comparisons.Frontiers in psychiatry · 2018Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although literature evidence suggests deficits in social and non-social cognition in patients with autistic spectrum disorder (ASD) and schizophrenia (SCZ), the difference in neural correlates of the impairments between the two disorders has not been elucidated. We examined brain function in response to a non-social cognition and a social cognition task using functional near-infrared spectroscopy (fNIRS) in 13 patients with ASD, 15 patients with SCZ, and 18 healthy subjects. We assessed the brain function of participants using a verbal fluency task and an emotional facial recognition task. The patients with ASD showed significantly reduced brain activation in the left frontotemporal area during both tasks compared to healthy subjects. The patients with ASD with larger score in 'attention to detail' in the autism spectrum quotient showed lower activation of the left frontotemporal area during the two tasks. The patients with SCZ showed significantly reduced activation, compared to healthy subjects, and greater activation, compared to patients with ASD, in the area during the verbal fluency task. The patients with SCZ with more severe symptoms had lower brain activation during the task in this area. Our results suggest that two distinct areas are involved in the distinctive brain pathophysiology relevant to cognitive processing in patients with ASD and SCZ.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.