Evidence map›Paper›PMID 29445073›Full record

ArticleThe Journal of veterinary medical science2018

Adiponectin deficiency-induced diabetes increases TNFα and FFA via downregulation of PPARα.

Haruo Hashimoto, Masafumi Yamamoto, Emika Sugiura, Hayato Abe, Takahiro Kagawa, Motohito Goto, Ri-Ichi Takahashi, Toshio Akimoto, Hiroshi Suemizu

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Haruo HashimotoCentral Institute for Experimental Animals, 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-0821, Japan.
Masafumi YamamotoCentral Institute for Experimental Animals, 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-0821, Japan.
Emika SugiuraCentral Institute for Experimental Animals, 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-0821, Japan.
Hayato AbeCentral Institute for Experimental Animals, 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-0821, Japan.
Takahiro KagawaCentral Institute for Experimental Animals, 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-0821, Japan.
Motohito GotoCentral Institute for Experimental Animals, 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-0821, Japan.
Ri-Ichi TakahashiCentral Institute for Experimental Animals, 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-0821, Japan.
Toshio AkimotoDivision of Laboratory Animal Science, Nippon Medical School, 115 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
Hiroshi SuemizuCentral Institute for Experimental Animals, 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-0821, Japan.
Central Institute for Experimental Animals · JPNippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Expression of peroxisome proliferator-activated receptor (PPAR) α was investigated in adiponectin knockout mice to elucidate the relationship between PPARα and adiponectin deficiency-induced diabetes. Adiponectin knockout (Adp

Indexed as

AdiponectinAnimalsDiabetes MellitusDown-RegulationFatty Acids, NonesterifiedGene Expression RegulationGlucose IntoleranceInsulinMiceMice, KnockoutPPAR alphaTumor Necrosis Factor-alphaAdiponectinFatty Acids, NonesterifiedInsulinPPAR alphaTumor Necrosis Factor-alphaadiponectindiabetesPPARα

Identifiers

PMID29445073
PMCPMC5938197
OpenAlexW2785328143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.