Evidence map›Paper›PMID 29445038›Full record

ArticleJournal of the Royal Society, Interface2018

Quantitative modelling of nutrient-limited growth of bacterial colonies in microfluidic cultivation.

Raphael Hornung, Alexander Grünberger, Christoph Westerwalbesloh, Dietrich Kohlheyer, Gerhard Gompper, Jens Elgeti

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. A Hamilton principle-based model for diffusion-driven biofilm growth.Biomechanics and modeling in mechanobiology · 2024
    Article
  4. Article
  5. Assessing the growth kinetics and stoichiometry ofEngineering in life sciences · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Raphael HornungTheoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich and JARA, 52425 Jülich, Germany.ORCID 0000-0002-6729-7289
Alexander GrünbergerInstitute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, 52425 Jülich, Germany.ORCID 0000-0002-7564-4957
Christoph WesterwalbeslohInstitute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, 52425 Jülich, Germany.ORCID 0000-0002-3064-7425
Dietrich KohlheyerInstitute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, 52425 Jülich, Germany.ORCID 0000-0001-6215-1857
Gerhard GompperTheoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich and JARA, 52425 Jülich, Germany.ORCID 0000-0002-8904-0986
Jens ElgetiTheoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich and JARA, 52425 Jülich, Germany j.elgeti@fz-juelich.de.ORCID 0000-0001-7300-0923
Forschungszentrum Jülich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutrient gradients and limitations play a pivotal role in the life of all microbes, both in their natural habitat as well as in artificial, microfluidic systems. Spatial concentration gradients of nutrients in densely packed cell configurations may locally affect the bacterial growth leading to heterogeneous micropopulations. A detailed understanding and quantitative modelling of cellular behaviour under nutrient limitations is thus highly desirable. We use microfluidic cultivations to investigate growth and microbial behaviour of the model organism

Indexed as

Computer SimulationMicrofluidicsModels, BiologicalCorynebacterium glutamicumbacterial nutrient consumptiongrowth simulationsmicrofluidic cultivationnutrient gradients

Identifiers

PMID29445038
PMCPMC5832723
OpenAlexW2785903641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.