Evidence map›Paper›PMID 29444836›Full record

ArticleJournal of clinical microbiology2018

Evaluation of the Elecsys Chagas Assay for Detection of Trypanosoma cruzi-Specific Antibodies in a Multicenter Study in Europe and Latin America.

Maria Delmans Flores-Chavez, Vittorio Sambri, Volkmar Schottstedt, Fernando Aparicio Higuera-Escalante, Dieter Roessler, Monica Chaves, Tina Laengin, Alfredo Martinez, Bernhard Fleischer

Open access · hybridAbstract readComparative StudyEvaluation StudyMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Evaluation of Chagas TESA VirClia assay for chronicJournal of clinical microbiology · 2026
    Article
  3. Performance of Elecsys Anti-HEV IgG and IgM Assays for the Detection of Acute, Recent or Past Hepatitis E Virus Infection.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Frontiers in microbiology · 2024
    Article
  8. Laboratory diagnosis ofFrontiers in parasitology · 2023
    Review
  9. Evaluation of the Chagas VirCliaPathogens (Basel, Switzerland) · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Chagas Disease: Detection ofJournal of clinical medicine · 2020
    Article
  16. Article
  17. Clinical and epidemiological aspects of chronic Chagas disease from Southern Brazil.Revista da Sociedade Brasileira de Medicina Tropical · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Maria Delmans Flores-ChavezUnit of Leishmaniasis and Chagas Disease, Department of Parasitology, National Microbiology Centre (CNM), Instituto de Salud Carlos III, Madrid, Spain mflores@externos.isciii.es.
Vittorio SambriUnit of Microbiology, Greater Romagna Hub Laboratory, AUSL della Romagna, Pievesestina, Cesena, Italy.
Volkmar SchottstedtGerman Red Cross Blood Transfusion Service West, Central Laboratory, Hagen, Germany.
Fernando Aparicio Higuera-EscalanteBlood Bank Higuera-Escalante, Bucaramanga, Colombia.
Dieter RoesslerRoche Diagnostics GmbH, Penzberg, Germany.
Monica ChavesProductos Roche SA, Bogotá, Colombia.
Tina LaenginRoche Diagnostics GmbH, Penzberg, Germany.
Alfredo MartinezCentro de Educación Médica e Investigaciones Clínicas Dr. Norberto Quirno, Buenos Aires, Argentina.
Bernhard FleischerNational Reference Centre for Tropical Infectious Agents, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Roche Pharma AG (Germany) · DEAzienda Unità Sanitaria Locale Della Romagna · ITBernhard Nocht Institute for Tropical Medicine · DECentro de Educación Médica e Investigaciones Clínicas Norberto Quirno · ARGerman Red Cross · DEInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serology is the preferred method to confirm a Chagas disease diagnosis and to screen blood donors. A battery of assays is often required due to the limited accuracy of single assays. The Elecsys Chagas assay is a newly developed, double-antigen sandwich assay for use on the Elecsys and cobas e immunoassay analyzers, intended to identify individuals infected with

Indexed as

Antibodies, ProtozoanChagas DiseaseEuropeFemaleHumansImmunoassayLatin AmericaMalePregnancySensitivity and SpecificitySerologic TestsTrypanosoma cruziAntibodies, ProtozoanChagas diseaseelectrochemiluminescence immunoassayserologyTrypanosoma cruzi

Identifiers

PMID29444836
PMCPMC5925710
OpenAlexW2789861810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.