Evidence map›Paper›PMID 29444824›Full record

ReviewThe Journal of biological chemistry2018

Kinesin-2 motors: Kinetics and biophysics.

Susan P Gilbert, Stephanie Guzik-Lendrum, Ivan Rayment

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. The kinesin KIF3AC recycles endocytosed integrin to polarize new adhesion formation toward the leading edge.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  12. Visualizing Vesicle-Bound Kinesins in Cultured Hippocampal Neurons.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  13. Intraflagellar transport trains and motors: Insights from structure.Seminars in cell & developmental biology · 2020
    Review
  14. Article
  15. The mechanochemistry of the kinesin-2 KIF3AC heterodimer is related to strain-dependent kinetic properties of KIF3A and KIF3C.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Susan P GilbertFrom the Department of Biological Sciences and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180 and sgilbert@rpi.edu.ORCID 0000-0002-7823-3774
Stephanie Guzik-LendrumFrom the Department of Biological Sciences and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180 and.
Ivan Raymentthe Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706 ivan_rayment@biochem.wisc.edu.ORCID 0000-0001-9279-7835
Rensselaer Polytechnic Institute · USUniversity of Wisconsin–Madison · US

Funding

Mechanistic Analysis of Microtubule Based MotorsR37GM054141 · NIGMS · RENSSELAER POLYTECHNIC INSTITUTE · PI GILBERT, SUSAN P. · 2013 to 2022
$4.4M
NIGMS NIH HHS R37 GM054141
6 · The paper itself

Abstract

Kinesin-2s are major transporters of cellular cargoes. This subfamily contains both homodimeric kinesins whose catalytic domains result from the same gene product and heterodimeric kinesins with motor domains derived from two different gene products. In this Minireview, we focus on the progress to define the biochemical and biophysical properties of the kinesin-2 family members. Our understanding of their mechanochemical capabilities has been advanced by the ability to identify the kinesin-2 genes in multiple species, expression and purification of these motors for single-molecule and ensemble assays, and development of new technologies enabling quantitative measurements of kinesin activity with greater sensitivity.

Indexed as

Adenosine TriphosphateAnimalsBiophysicsHumansKinesinsKineticsMicrotubule-Associated ProteinsMicrotubulesAdenosine TriphosphateKIF2A protein, humanKinesinsMicrotubule-Associated ProteinsATPaseciliacytoskeletonintracellular traffickingmicrotubulemolecular motormotor proteinneuronpre-steady-state kineticsprocessivitysingle-molecule biophysicstubulin

Identifiers

PMID29444824
PMCPMC5868254
OpenAlexW2787751062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.