ArticleBMC pulmonary medicine2018
Patterns of pleural pressure amplitude and respiratory rate changes during therapeutic thoracentesis.
Article in BMC pulmonary medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02192138 (Ventilation, Gas Exchange and Cardiac Function in Relation to Intrapleural Pressure Changes in Patients Undergoing Therapeutic Thoracentesis), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ventilation, Gas Exchange and Cardiac Function in Relation to Intrapleural Pressure Changes in Patients Undergoing Therapeutic Thoracentesis
Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Hemidiaphragm work in large pleural effusion and its insignificant impact on blood gases: a new insight based onFrontiers in physiology · 2025Article
- Increased work of breathing and its relationship to dyspnea in malignant pleural effusion.Frontiers in physiology · 2025Article
- The impact of spontaneous cough on pleural pressure changes during therapeutic thoracentesis.Scientific reports · 2022Article
- Independent Lung Ventilation-Experimental Studies on a 3D Printed Respiratory Tract Model.Materials (Basel, Switzerland) · 2021Article
- Pleural Pressure Pulse in Patients with Pleural Effusion: A New Phenomenon Registered during Thoracentesis with Pleural Manometry.Journal of clinical medicine · 2020Article
- Pleural manometry: techniques, applications, and pitfalls.Journal of thoracic disease · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAlthough the impact of therapeutic thoracentesis on lung function and blood gases has been evaluated in several studies, some physiological aspects of pleural fluid withdrawal remain unknown. The aim of the study was to assess the changes in pleural pressure amplitude (Ppl
methodsThe study included 23 patients with symptomatic pleural effusion. Baseline pleural pressure curves were registered with a digital electronic manometer. Then, the registrations were repeated after the withdrawal of consecutive portions of pleural fluid (200 ml up to 1000 ml and 100 ml above 1000 ml). In all patients the pleural pressure curves were analyzed in five points, at 0, 25%, 50%, 75% and 100% of the relative volume of pleural effusion withdrawn in particular patients.
resultsThere were 11 and 12 patients with right sided and left sided pleural effusion, respectively (14 M, 9F, median age 68, range 46-85 years). The most common cause of pleural effusion were malignancies (20 pts., 87%). The median total volume of withdrawn pleural fluid was 1800 (IQR 1500-2400) ml. After termination of pleural fluid withdrawal Ppl
conclusionsIn conclusion, therapeutic thoracentesis is associated with significant changes in Ppl
trial registrationClinicalTrial.gov, registration number: NCT02192138 , registration date: July 1st, 2014.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.