ReviewCurrent opinion in neurobiology2018
Challenges and opportunities for large-scale electrophysiology with Neuropixels probes.
Review in Current opinion in neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 177 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
177 citing papers in PubMed.
- A standardized and reproducible behavioral framework to elicit multiple aspects of visual spatial attention in mice.Cell reports methods · 2026Article
- Synaptic Organization of the Primate Retina: Toward a Human Foveal Connectome.Annual review of vision science · 2026Review
- An in silico framework for dissecting the mechanistic origins of in vivo recorded neuronal activity.PLoS computational biology · 2026Article
- Large-Scale Neural Recording Technologies for Investigating Circuit Dysfunction and Functional Biomarker Discovery in Animal Models of Alzheimer's Disease.International journal of molecular sciences · 2026Review
- Fast penalized generalized estimating equations for large longitudinal functional datasets.Biometrics · 2026Article
- BiXformer: A Bidirectional Cross Attention Transformer for Disentangling Inter-Regional Neural Dynamics.bioRxiv : the preprint server for biology · 2026Article
- Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Large-scale electrophysiology at single-spike resolution.Nature reviews. Neuroscience · 2026Review
- Simple input-output dependencies explain neuronal activity.Nature physics · 2026Article
- Extracellular Spike Waveforms: Morphology, Biophysics, and Classification Strategies.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- Developmental and aging changes in brain network switching dynamics revealed by EEG phase synchronization.PLoS computational biology · 2026Article
- Article
- A flexible quality metric for electrophysiological recordings across brain regions and species.bioRxiv : the preprint server for biology · 2026Article
- OP-GLX: A MATLAB Toolbox for Online Processing and Plotting of Neuropixels Data Acquired with SpikeGLX.bioRxiv : the preprint server for biology · 2026Article
- Optimizing electrode placement and information capacity for local field potentials in cortex.NeuroImage · 2026Article
- Optimal inter-electrode distances for maximizing single unit yield per electrode in neural recordings.Microsystems & nanoengineering · 2026Article
- Cross-population amplitude coupling in high-dimensional oscillatory neural time series.Frontiers in computational neuroscience · 2026Article
- Long-term neuron tracking reveals balance of stability and plasticity in functional properties.PloS one · 2026Article
- An adaptive and flexible role for primary sensory cortex.Nature neuroscience · 2026Review
- A standardized and reproducible behavioral protocol to elicit visual spatial attention in mice.bioRxiv : the preprint server for biology · 2025Article
117 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
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Abstract
Electrophysiological methods are the gold standard in neuroscience because they reveal the activity of individual neurons at high temporal resolution and in arbitrary brain locations. Microelectrode arrays based on complementary metal-oxide semiconductor (CMOS) technology, such as Neuropixels probes, look set to transform these methods. Neuropixels probes provide ∼1000 recording sites on an extremely narrow shank, with on-board amplification, digitization, and multiplexing. They deliver low-noise recordings from hundreds of neurons, providing a step change in the type of data available to neuroscientists. Here we discuss the opportunities afforded by these probes for large-scale electrophysiology, the challenges associated with data processing and anatomical localization, and avenues for further improvements of the technology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.