Evidence map›Paper›PMID 29444243›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2018

Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project.

Kathrin Blagec, Rudolf Koopmann, Mandy Crommentuijn-van Rhenen, Inge Holsappel, Cathelijne H van der Wouden, Lidija Konta, Hong Xu, Daniela Steinberger, Enrico Just, Jesse J Swen and 2 more

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Genetically guided precision medicine clinical decision support tools: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2024
    Pooled it
  3. Trial
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Review
  10. Population health management of human phenotype ontology.Frontiers in artificial intelligence · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Advancing Pharmacogenomics from Single-Gene to Preemptive Testing.Annual review of genomics and human genetics · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kathrin BlagecSection for Artificial Intelligence and Decision Support; Center for Medical Statistics, Informatics, and Intelligent Systems; Medical University of Vienna, Vienna, Austria.
Rudolf Koopmannbio.logis Genetic Information Management GmbH, Frankfurt am Main, Germany.
Mandy Crommentuijn-van RhenenMedicines Information Centre; Royal Dutch Pharmacists Association (KNMP), The Hague, The Netherlands.
Inge HolsappelMedicines Information Centre; Royal Dutch Pharmacists Association (KNMP), The Hague, The Netherlands.
Cathelijne H van der WoudenDeptartment of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
Lidija Kontabio.logis Center for Human Genetics, Frankfurt am Main, Germany.
Hong XuSection for Artificial Intelligence and Decision Support; Center for Medical Statistics, Informatics, and Intelligent Systems; Medical University of Vienna, Vienna, Austria.
Daniela Steinbergerbio.logis Genetic Information Management GmbH, Frankfurt am Main, Germany.
Enrico Justbio.logis Genetic Information Management GmbH, Frankfurt am Main, Germany.
Jesse J SwenDeptartment of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
Henk-Jan GuchelaarDeptartment of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
Matthias SamwaldSection for Artificial Intelligence and Decision Support; Center for Medical Statistics, Informatics, and Intelligent Systems; Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support tools, which is often hampered by insufficient or fragmented infrastructures. This paper describes the setup and implementation of a unique multimodal, multilingual clinical decision support intervention consisting of digital, paper-, and mobile-based tools that are deployed across implementation sites in seven European countries participating in the Ubiquitous PGx (U-PGx) project.

Indexed as

Decision Support Systems, ClinicalPharmacogeneticsEuropeHumansKnowledge BasesMobile ApplicationsMultilingualism

Identifiers

PMID29444243
PMCPMC6016647

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.