ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018
Association of Neighborhood Socioeconomic Status With Risk of Infection and Sepsis.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Rapid systematic review on risks and outcomes of sepsis: the influence of risk factors associated with health inequalities.International journal for equity in health · 2024Pooled it
- Association Between Community-Level Social Determinants of Health and Sepsis Incidence and Mortality: A Scoping Review.Critical care explorations · 2026Article
- Mitigating Bias in Machine Learning Models with Ethics-Based Initiatives: The Case of Sepsis.The American journal of bioethics : AJOB · 2026Article
- Assessing the association between elements of health inequalities and the risk of bacterial infection in high-income countries: a systematic scoping review.Access microbiology · 2026Review
- Racial Disparities in Septic Shock Outcomes: A Nationwide Analysis (2016-2020).Journal of general internal medicine · 2025Article
- Article
- Provider-to-provider telemedicine for sepsis is used less frequently in communities with high social vulnerability.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025Article
- Social Determinants of Health and Risk-Adjusted Sepsis Mortality in the Nationwide Veterans Affairs Healthcare System.Journal of general internal medicine · 2024Observational
- Race and Ethnicity Disparities in Management and Outcomes of Critically Ill Adults with Acute Respiratory Failure.Critical care clinics · 2024Review
- Social determinants of health and sepsis: a case-control study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Article
- Risk assessment with gene expression markers in sepsis development.Cell reports. Medicine · 2024Article
- Article
- Clinical and health inequality risk factors for non-COVID-related sepsis during the global COVID-19 pandemic: a national case-control and cohort study.EClinicalMedicine · 2023Article
- The effects of sociodemographic factors and comorbidities on sepsis: A nationwide Swedish cohort study.Preventive medicine reports · 2023Article
- Comparison of Oral and Intravenous Definitive Antibiotic Therapy for Beta-Hemolytic Streptococcus Species Bloodstream Infections from Soft Tissue Sources: a Propensity Score-Matched Analysis.Antimicrobial agents and chemotherapy · 2023Article
- Associations of socioeconomic status with infectious diseases mediated by lifestyle, environmental pollution and chronic comorbidities: a comprehensive evaluation based on UK Biobank.Infectious diseases of poverty · 2023Article
- Observational
- Home-to-hospital distance and outcomes among community-acquired sepsis hospitalizations.Annals of epidemiology · 2022Article
- Social Determinants of Health Associated With the Development of Sepsis in Adults: A Scoping Review.Critical care explorations · 2022Article
- Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.Intensive care medicine · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Background: Prior studies suggest disparities in sepsis risk and outcomes based on place of residence. We sought to examine the association between neighborhood socioeconomic status (nSES) and hospitalization for infection and sepsis. Methods: We conducted a prospective cohort study using data from 30239 participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. nSES was defined using a score derived from census data and classified into quartiles. Infection and sepsis hospitalizations were identified over the period 2003-2012. We fit Cox proportional hazards models, reporting hazard ratios (HRs) with 95% confidence intervals (CIs) and examining mediation by participant characteristics. Results: Over a median follow-up of 6.5 years, there were 3054 hospitalizations for serious infection. Infection incidence was lower for participants in the highest nSES quartile compared with the lowest quartile (11.7 vs 15.6 per 1000 person-years). After adjustment for demographics, comorbidities, and functional status, infection hazards were also lower for the highest quartile (HR, 0.84 [95% CI, .73-.97]), with a linear trend (P = .011). However, there was no association between nSES and sepsis at presentation among those hospitalized with infection. Physical weakness, income, and diabetes had modest mediating effects on the association of nSES with infection. Conclusions: Our study shows that differential infection risk may explain nSES disparities in sepsis incidence, as higher nSES is associated with lower infection hospitalization rates, but there is no association with sepsis among those hospitalized. Mediation analysis showed that nSES may influence infection hospitalization risk at least partially through physical weakness, individual income, and comorbid diabetes.
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