ArticlePloS one2018
Exploration of avocado by-products as natural sources of bioactive compounds.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
60 citing papers in PubMed, 231 citations in OpenAlex.
- Changes in Phenolic Compounds, Antioxidant Capacity, Color, and Microstructure of Hass Avocado (Molecules (Basel, Switzerland) · 2026Article
- Advances In the Valorization of Avocado By-Products: Bioactive Compounds, Techno-Functional Properties, and Structure-Function Relationships.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026Review
- Bioprospecting Underutilized Plant By-Products for Antioxidant Natural Extracts: A Review.Molecules (Basel, Switzerland) · 2026Review
- Contribution of Phenolic Acid Profiles to the Anti-Adipogenic Activity of DifferentBiomedicines · 2026Article
- Gamma radiation assisted reduction of graphene oxide inNanoscale advances · 2026Article
- Comparative Anticancer Activity of Extract, Partitions, and a Two-Acetogenin Mixture from Mexican Creole Avocado Seed.Molecules (Basel, Switzerland) · 2026Article
- In vitro anti-inflammatory potential and in vivo anti-arthritis activities of Ximenia caffra extract on antigen-induced arthritis in rats.Scientific reports · 2026Article
- Linking fatty acid composition to enzyme inhibition supported by molecular docking, alongside multifunctional bioactivities, of avocado, Indian mustard, and passion fruit seed oils.Frontiers in nutrition · 2026Article
- Phytochemical Characterization and Anticancer Potential of Avocado Seed Oil.Chemistry & biodiversity · 2026Article
- Oral Delivery of Avocado Peel Extract Using Albumin Nanocarriers to Modulate Cholesterol Absorption.Pharmaceutics · 2025Article
- Carnauba Wax Coatings Enriched with Essential Oils or Fruit By-Products Reduce Decay and Preserve Postharvest Quality in Organic Citrus.Foods (Basel, Switzerland) · 2025Article
- Bioactive Properties ofFoods (Basel, Switzerland) · 2025Article
- Optimization of Extraction Parameters for Phenolics Recovery from Avocado Peels Using Ultrasound and Microwave Technologies.Foods (Basel, Switzerland) · 2025Article
- Article
- Sustainable Extraction Technology of Fruit and Vegetable Residues as Novel Food Ingredients.Foods (Basel, Switzerland) · 2025Review
- Drying kinetic models, thermodynamics, physicochemical qualities, and bioactive compounds of avocado (Heliyon · 2025Article
- Toxicological qualities and detoxification trends of fruit by-products for valorization: A review.Open life sciences · 2025Review
- Avocado (Frontiers in nutrition · 2025Review
- The Pulp, Peel, Seed, and Food Products ofInternational journal of molecular sciences · 2024Review
- Polymorphism and Microstructural Changes in Avocado Pulp (Foods (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to evaluate the antioxidant, anti-inflammatory, and cytotoxic properties and phenolic composition of peel and seed of avocado varieties Hass and Fuerte using green solvents. Ethanol soluble compounds were identified in peel and seed of both varieties using HPLC-MS/MS and quantified using HPLC-DAD. Agro-industrial by-products of both varieties exhibited high radical scavenging activity against synthetic free radicals (DPPH and ABTS) and reactive oxygen species (peroxyl, superoxide, and hypochlorous acid) and high ability to reduce Fe3+ to Fe2+. The main compounds with significant contribution to the antioxidant activity determined by online HPLC-ABTS●+ analyses were procyanidin B2 and epicatechin in the peel and trans-5-O-caffeoyl-D-quinic acid, procyanidin B1, catechin, and epicatechin in the seed. Peel of Fuerte significantly suppressed TNF-α and nitric oxide (NO) release (459.3 pg/mL and 8.5 μM, respectively), possibly because of the high phenolic content and antioxidant activity detected. Avocado agro-industrial by-products can be used for food and pharmaceutical purposes due to their antioxidant and anti-inflammatory properties.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.