ArticleOptics letters2018
Label-free cell nuclear imaging by Grüneisen relaxation photoacoustic microscopy.
Article in Optics letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Multifocal Optical-Resolution Photoacoustic Microscopy With a Masked Single-Element Transducer.IEEE transactions on medical imaging · 2026Article
- Sound Out the Deep Clarity: Super-Resolution Photoacoustic Imaging at Depths.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024Review
- Rapid and label-free histological imaging of unprocessed surgical tissues via dark-field reflectance ultraviolet microscopy.iScience · 2023Article
- Visualizing tumor angiogenesis and boundary with polygon-scanning multiscale photoacoustic microscopy.Photoacoustics · 2022Article
- Ultraviolet photoacoustic microscopy with tissue clearing for high-contrast histological imaging.Photoacoustics · 2022Article
- Single laser-shot super-resolution photoacoustic tomography with fast sparsity-based reconstruction.Photoacoustics · 2021Article
- Nonlinear mechanisms in photoacoustics-Powerful tools in photoacoustic imaging.Photoacoustics · 2021Review
- Listening to tissues with new light: recent technological advances in photoacoustic imaging.Journal of optics (2010) · 2019Article
- Review on practical photoacoustic microscopy.Photoacoustics · 2019Review
- Dual-view photoacoustic microscopy for quantitative cell nuclear imaging.Optics letters · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Photoacoustic microscopy (PAM) with ultraviolet (UV) laser illumination has recently been demonstrated as a promising tool that provides fast, label-free, and multilayered histologic imaging of human breast tissue. Thus far, the axial resolution has been determined ultrasonically. To enable optically defined axial resolution, we exploit the Grüneisen relaxation (GR) effect. By imaging mouse brain slices, we show that GRUV-PAM reveals detailed information about three-dimensional cell nuclear distributions and internal structures, which are important diagnostic features for cancers. Due to the nonlinear effect, GRUV-PAM also provides better contrast in images of cell nuclei.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.