ReviewViruses2018
Mosquitoes as Suitable Vectors for Alphaviruses.
Review in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Autoantibodies and Molecular Mimicry in Alphavirus Chronic Arthritis: A Systematic Review.Pathogens (Basel, Switzerland) · 2026Pooled it
- Development ofEmerging microbes & infections · 2025Article
- Viral epidemic potential is not uniformly distributed across the bat phylogeny.Communications biology · 2025Article
- Neuropathogenesis of Old World Alphaviruses: Considerations for the Development of Medical Countermeasures.Viruses · 2025Review
- Balancing functions of regulatory T cells in mosquito-borne viral infections.Emerging microbes & infections · 2024Review
- TRIM32 inhibits Venezuelan equine encephalitis virus infection by targeting a late step in viral entry.PLoS pathogens · 2024Article
- Emergence of ECSA-IOL E1-K211E/E2-V264A Lineage of Chikungunya virus during Malaysian 2021 outbreak.BMC infectious diseases · 2024Article
- TRIM32 inhibits Venezuelan Equine Encephalitis Virus Infection by targeting a late step in viral entry.bioRxiv : the preprint server for biology · 2024Article
- Article
- Dengue and chikungunya virus loads in the mosquito Aedes aegypti are determined by distinct genetic architectures.PLoS pathogens · 2023Article
- Review
- Article
- Visualization of the Oncolytic Alphavirus M1 Life Cycle in Cancer Cells.Virologica Sinica · 2021Article
- Persistent Joint Pain Following Arthropod Virus Infections.Current rheumatology reports · 2021Review
- Molecular Epidemiology, Evolution and Reemergence of Chikungunya Virus in South Asia.Frontiers in microbiology · 2021Review
- Interepidemic Detection of Chikungunya Virus Infection and Transmission in Northeastern Thailand.The American journal of tropical medicine and hygiene · 2020Article
- Article
- Immunopathogenesis of alphaviruses.Advances in virus research · 2020Article
- Mosquito antiviral defense mechanisms: a delicate balance between innate immunity and persistent viral infection.Parasites & vectors · 2019Review
- A scoping review of Chikungunya virus infection: epidemiology, clinical characteristics, viral co-circulation complications, and control.Acta tropica · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alphaviruses are arthropod-borne viruses and are predominantly transmitted via mosquito vectors. This vector preference by alphaviruses raises the important question of the determinants that contribute to vector competence. There are several tissue barriers of the mosquito that the virus must overcome in order to establish a productive infection. Of importance are the midgut, basal lamina and the salivary glands. Infection of the salivary glands is crucial for virus transmission during the mosquito's subsequent bloodfeed. Other factors that may contribute to vector competence include the microflora and parasites present in the mosquito, environmental conditions, the molecular determinants of the virus to adapt to the vector, as well as the effect of co-infection with other viruses. Though mosquito innate immunity is a contributing factor to vector competence, it will not be discussed in this review. Detailed understanding of these factors will be instrumental in minimising transmission of alphaviral diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.