Evidence map›Paper›PMID 29443358›Full record

ArticleOphthalmic surgery, lasers & imaging retina2018

Microscope-Integrated Intraoperative Ultrahigh-Speed Swept-Source Optical Coherence Tomography for Widefield Retinal and Anterior Segment Imaging.

Chen D Lu, Nadia K Waheed, Andre Witkin, Caroline R Baumal, Jonathan J Liu, Benjamin Potsaid, Anthony Joseph, Vijaysekhar Jayaraman, Alex Cable, Kinpui Chan and 2 more

Abstract read
In one paragraph

Article in Ophthalmic surgery, lasers & imaging retina, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. [Real-time optical coherence tomography-assisted high-precision vitreoretinal surgery in the clinical routine].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chen D Lu
Nadia K Waheed
Andre Witkin
Caroline R Baumal
Jonathan J Liu
Benjamin Potsaid
Anthony Joseph
Vijaysekhar Jayaraman
Alex Cable
Kinpui Chan
Jay S Duker
James G Fujimoto

Funding

Novel Optical Diagnostics with Optical Coherence TomographyR01EY011289 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI JAMES G FUJIMOTO · 1995 to 2026
$9.5M
VCSEL technology for ultrahigh speed OCT retinal and anterior eye imagingR44EY022864 · NEI · PRAEVIUM RESEARCH, INC. · PI JAYARAMAN, VIJAYSEKHAR · 2012 to 2014
$1.1M
NEI NIH HHS R01 EY011289NEI NIH HHS R44 EY022864
6 · The paper itself

Abstract

BACKGROUND AND

objectiveTo demonstrate the feasibility of retinal and anterior segment intraoperative widefield imaging using an ultrahigh-speed, swept-source optical coherence tomography (SS-OCT) surgical microscope attachment. PATIENTS AND

methodsA prototype post-objective SS-OCT using a 1,050-nm wavelength, 400 kHz A-scan rate, vertical cavity surface-emitting laser (VCSEL) light source was integrated to a commercial ophthalmic surgical microscope after the objective. Each widefield OCT data set was acquired in 3 seconds (1,000 × 1,000 A-scans, 12 × 12 mm

resultsIntraoperative SS-OCT was performed in 20 eyes of 20 patients. In six of seven membrane peels and five of seven rhegmatogenous retinal detachment repair surgeries, widefield retinal imaging enabled evaluation pre- and postoperatively. In all seven cataract cases, anterior imaging evaluated the integrity of the posterior lens capsule.

conclusionsUltrahigh-speed SS-OCT enables widefield intraoperative viewing in the posterior and anterior eye. Widefield imaging visualizes ocular structures and pathology without requiring OCT realignment. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:94-102.].

Indexed as

AgedAged, 80 and overAnterior Eye SegmentCataract ExtractionFeasibility StudiesFemaleHumansIntraoperative PeriodMaleMicroscopyMiddle AgedOptical ImagingRetinal DiseasesTomography, Optical CoherenceVitrectomy

Identifiers

PMID29443358
PMCPMC6345381

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.