ReviewNeurology. Clinical practice2016
Stroke due to large vessel atherosclerosis: Five new things.
Review in Neurology. Clinical practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and safety of tirofiban in acute ischemic stroke due to intracranial atherosclerotic disease for patients undergoing endovascular treatment: a systematic review and meta-analysis.Neuroradiology · 2025Pooled it
- Effect of Individualized Coaching at Home on Quality of Life in Subacute Stroke Patients.International journal of environmental research and public health · 2023Trial
- Extracellular Vesicles in Stroke: Drivers of Brain-Body Network Crosstalk.Translational stroke research · 2026Review
- Real-time phase-contrast MRI can be used to quantify cerebrovascular reserve capacity - a comparative study to neurovascular ultrasound in healthy subjects.Neuroimage. Reports · 2026Article
- Inflammatory Biomarkers and Carotid Atherosclerosis: The Predictive Role of the Neutrophil/Albumin Ratio.Medicina (Kaunas, Lithuania) · 2025Article
- Serum from Stroke Patients with High-Grade Carotid Stenosis Promotes Cyclooxygenase-Dependent Endothelial Dysfunction in Non-ischemic Mice Carotid Arteries.Translational stroke research · 2024Article
- Genetics in Ischemic Stroke: Current Perspectives and Future Directions.Journal of cardiovascular development and disease · 2023Review
- Association of Genetic and Allelic Variants of Von Willebrand Factor (VWF), Glutathione S-Transferase and Tumor Necrosis Factor Alpha with Ischemic Stroke Susceptibility and Progression in the Saudi Population.Life (Basel, Switzerland) · 2023Article
- New strategy for clinical etiologic diagnosis of acute ischemic stroke and blood biomarker discovery based on machine learning.RSC advances · 2022Article
- Ionizing radiation, cerebrovascular disease, and consequent dementia: A review and proposed framework relevant to space radiation exposure.Frontiers in physiology · 2022Review
- A novel integrated angioscope-laser system for atherosclerotic carotid artery occlusion: Feasibility and techniques.Frontiers in surgery · 2022Article
- Matrix Metalloproteinase-9 Gene Polymorphism and Its Methylation in Stroke Patients.The Malaysian journal of medical sciences : MJMS · 2021Article
- A Narrative Review of Contemporary Global Perspectives into Epidemiology, Treatment, and Prognosis of Vertebrobasilar Strokes.Rwanda journal of medicine and health sciences · 2021Review
- Prevalence and correlates of carotid artery stenosis in a cohort of Sri Lankan ischaemic stroke patients.BMC neurology · 2021Article
- Cardio-Ankle Vascular Index Predicts Post-Discharge Stroke in Patients with Heart Failure.Journal of atherosclerosis and thrombosis · 2021Observational
- Polyphenols and Ischemic Stroke: Insight into One of the Best Strategies for Prevention and Treatment.Nutrients · 2021Review
- Early and long-term prognosis in patients with and without type 2 diabetes after carotid intervention: a Swedish nationwide propensity score matched cohort study.Cardiovascular diabetology · 2021Observational
- Outcomes of Ischemic Stroke and Associated Factors Among Elderly Patients With Large-Artery Atherosclerosis: A Hospital-Based Follow-Up Study in China.Frontiers in neurology · 2021Article
- MicroRNA-214 modulates the senescence of vascular smooth muscle cells in carotid artery stenosis.Molecular medicine (Cambridge, Mass.) · 2020Article
- The Prognostic Value of High Platelet Reactivity in Ischemic Stroke Depends on the Etiology: A Pilot Study.Journal of clinical medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewExtracranial (EC) and intracranial (IC) large vessel atherosclerosis account for about 20% of ischemic stroke cases. In recent years, new treatments have emerged for treatment of both EC and IC disease. RECENT
findingsThe stroke rate in patients with carotid stenosis is decreasing with modern medical therapy. For patients with asymptomatic stenosis, the stroke rate is likely <1% per year. Some subsets of patients with symptomatic carotid disease benefit less from revascularization, and medical management can be considered in these patients. A second clinical trial has confirmed that aggressive medical management is the treatment of choice for IC atherosclerotic disease. Vessel wall imaging may be useful to define pathophysiology in patients with IC stenosis and could ultimately help tailor therapy, but further studies are needed. Medical therapy is preferred to stenting for patients with vertebral artery-origin stenosis. SUMMARY: Recent data and emerging concepts regarding large vessel atherosclerosis are provided.
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