ArticleEnvironmental science and pollution research international2018
Protective effect of Uncaria tomentosa extract against oxidative stress and genotoxicity induced by glyphosate-Roundup® using zebrafish (Danio rerio) as a model.
Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 44 citations in OpenAlex.
- Review
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- Antigenotoxic Effect of Ascorbic Acid and Resveratrol in Erythrocytes ofCurrent issues in molecular biology · 2022Article
- Exploring CNS Effects of American Traditional Medicines using Zebrafish Models.Current neuropharmacology · 2022Article
- Acute exposition to Roundup Transorb® induces systemic oxidative stress and alterations in the expression of newly sequenced genes in silverside fish (Odontesthes humensis).Environmental science and pollution research international · 2021Article
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- Changes in Human Erythrocyte Membrane Exposed to Aqueous and Ethanolic Extracts fromMolecules (Basel, Switzerland) · 2021Article
- Probiotic antigenotoxic activity as a DNA bioprotective tool: a minireview with focus on endocrine disruptors.FEMS microbiology letters · 2020Review
- Antioxidant Activity of an Aqueous Leaf Extract fromMolecules (Basel, Switzerland) · 2019Article
- Glyphosate does not substitute for glycine in proteins of actively dividing mammalian cells.BMC research notes · 2019Article
- Iron and manganese present in underground water promote biochemical, genotoxic, and behavioral alterations in zebrafish (Danio rerio).Environmental science and pollution research international · 2019Article
- Protection of silver nanoparticles usingInternational journal of nanomedicine · 2018Article
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 1 country.
Funding
Abstract
Oxidative stress and DNA damage are involved in the glyphosate-based herbicide toxicity. Uncaria tomentosa (UT; Rubiaceae) is a plant species from South America containing bioactive compounds with known beneficial properties. The objective of this work was to evaluate the antioxidant and antigenotoxic potential of UT extract in a model of acute exposure to glyphosate-Roundup® (GR) in zebrafish (Danio rerio). We showed that UT (1.0 mg/mL) prevented the decrease of brain total thiols, the increase of lipid peroxidation in both brain and liver, and the decrease of liver GPx activity caused after 96 h of GR (5.0 mg/L) exposure. In addition, UT partially protected against the increase of micronucleus frequency induced by GR exposure in fish brain. Overall, our results indicate that UT protects against damage induced by a glyphosate-based herbicide by providing antioxidant and antigenotoxic effects, which may be related to the phenolic compounds identified in the extract.
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Registered trials
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