ArticleAsian journal of andrology
Erectile dysfunction is associated with subclinical carotid vascular disease in young men lacking widely-known risk factors.
Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- The impact of obesity and obstructive sleep apnea on vascular hemodynamics in men under 40: a 15-year retrospective cohort study.Sexual medicine · 2026Article
- Article
- Serum LDL level as an indirect marker of erectile dysfunction in male CAD patients.Journal of family medicine and primary care · 2025Article
- Association of relative fat mass with prevalence of erectile dysfunction in US men: an analysis of NHANES 2001-2004.International journal of impotence research · 2025Article
- Gout and erectile dysfunction: Increased carotid intima-media thickness is independently associated with greater likelihood for erectile dysfunction.Archives of rheumatology · 2024Article
- Serum folic acid: an effective indicator for arteriogenic erectile dysfunction.Frontiers in endocrinology · 2023Article
- Association of erectile dysfunction with coronary artery disease in Type 2 Diabetes mellitus.Ghana medical journal · 2023Observational
- Correlation analysis of carotid artery intima-media thickness, serum 25(OH)D and men with erectile dysfunction.Frontiers in endocrinology · 2022Article
- Prevalence of Erectile Dysfunction in Patients With Abdominal Aortic Aneurysm: An Exploratory Study.Frontiers in cardiovascular medicine · 2022Article
- Heart Rate Variability and Erectile Function in Younger Men: A Pilot Study.Applied psychophysiology and biofeedback · 2021Article
- Analysis of cardiovascular risks for erectile dysfunction in Chinese patients with type 2 diabetes mellitus lacking clinical symptoms of cardiovascular diseases.Translational andrology and urology · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to gain insight into the underlying pathogenesis of erectile dysfunction in young men under the age of 40 years without widely-known risk factors. Compared with normal controls, patients with erectile dysfunction had increased carotid intima-media thickness, fasting levels of blood glucose and insulin, and homeostatic model assessment index, as well as lower flow-mediated vasodilation and testosterone levels (P < 0.05), though all of these values were within their respective normal range. Multivariate logistic regression analysis identified carotid intima-media thickness, flow-mediated vasodilation, insulin level, and homeostatic model assessment index as significant predictors of erectile dysfunction. Young men with flow-mediated vasodilation <10.65% were 11.645 times more likely to have erectile dysfunction, young men with carotid intima-media thickness >0.623 mm had a 4.16-fold, and young men with homeostatic model assessment index >1.614 had a 5.993-fold greater risk of having erectile dysfunction. In conclusions, in young men with normal results from general clinical screening, an increased carotid intima-media thickness and homeostatic model assessment index and reduced flow-mediated vasodilation were associated with a higher incidence of erectile dysfunction. Erectile dysfunction may appear before the detection of traditional cardiovascular risk factors and may be the earliest clinical sign of subclinical cardiovascular disease.
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