Evidence map›Paper›PMID 29441597›Full record

ArticleResearch in nursing & health2018

Toxic stress and protective factors in multi-ethnic school age children: A research protocol.

Eileen M Condon, Lois S Sadler, Linda C Mayes

Abstract read
In one paragraph

Article in Research in nursing & health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
8.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eileen M CondonYale School of Nursing, Orange, Connecticut.ORCID 0000-0001-7747-5870
Lois S SadlerYale School of Nursing, Orange, Connecticut.
Linda C MayesYale Child Study Center, New Haven, Connecticut.
Yale University · US

Funding

Toxic Stress and Protective Factors in Multiethnic School Age ChildrenF31NR016385 · NINR · YALE UNIVERSITY · PI CONDON, EILEEN · 2016 to 2017
$80k
NINR NIH HHS F31 NR016385
6 · The paper itself

Abstract

Exposure to stressful environments in early childhood can cause a toxic stress response and lead to poor health outcomes, including obesity, cardiac disease, diabetes, and mental illness. In animals and maltreated children, the presence of a nurturing caregiver can buffer against the physiological disruptions associated with a toxic stress response; however, the specific caregiver and parenting characteristics that best promote a protective relationship in humans remain largely unexplored, particularly in families living in high-risk environments. In this study, framed in an ecobiodevelopmental (EBD) model, a cross-sectional design is being used to study 54 multi-ethnic, urban maternal-child dyads with children at early school age (4-9 years). Mothers' past experiences, mental health, and caregiving patterns and children's hair cortisol, C-reactive protein, pro-inflammatory cytokines, blood pressure, BMI, behavior, and school performance are being analyzed to identify maternal characteristics that may protect against children's toxic stress response in families at high risk for exposure to stressors such as poverty, trauma, or exposure to violence.

Indexed as

EthnicityProtective FactorsAdultChildChild, PreschoolChild WelfareCross-Sectional StudiesFemaleHumansMaleMental HealthMother-Child RelationsMothersStress, Psychologicalemotional states/feelingsfamily healthhealth promotion/wellness behaviorsparent-child relationshipspreventionstress and coping

Identifiers

PMID29441597
PMCPMC5989308
OpenAlexW2792968550

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.