ReviewHormones & cancer2018
Thyroid Hormone in the Clinic and Breast Cancer.
Review in Hormones & cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Benign thyroid disease and the risk of breast cancer: An updated systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Thyroid Hormone Treatment and Breast Cancer Risk in Women: A Systematic Review and Meta-Analysis of Observational Studies.Metabolites · 2026Review
- Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study.Journal of the National Cancer Institute · 2025Article
- Epithelial cell-related prognostic risk model in breast cancer based on single-cell and bulk RNA sequencing.Heliyon · 2024Article
- Article
- Thyroid hormone enhances estrogen-mediated proliferation and cell cycle regulatory pathways in steroid receptor-positive breast Cancer.Cell cycle (Georgetown, Tex.) · 2024Article
- The causal relationship between thyroid function, autoimune thyroid dysfunction and lung cancer: a mendelian randomization study.BMC pulmonary medicine · 2023Article
- Perfluoroalkyl substances (PFASs) as risk factors for breast cancer: a case-control study in Chinese population.Environmental health : a global access science source · 2022Article
- Is Melanoma Progression Affected by Thyroid Diseases?International journal of molecular sciences · 2022Review
- Cancer-specific mortality in breast cancer patients with hypothyroidism: a UK population-based study.Breast cancer research and treatment · 2022Article
- Hormonal Crosstalk Between Thyroid and Breast Cancer.Endocrinology · 2022Review
- Thyroid Diseases and Breast Cancer.Journal of personalized medicine · 2022Review
- Malignant neoplasms in people with hypothyroidism in Spain: A population-based analysis.PloS one · 2022Article
- Hypothyroidism has a protective causal association with hepatocellular carcinoma: A two-sample Mendelian randomization study.Frontiers in endocrinology · 2022Article
- (Thyroid) Hormonal regulation of breast cancer cells.Frontiers in endocrinology · 2022Review
- Leveraging Comprehensive Health Records for Breast Cancer Risk Prediction: A Binational Assessment.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2022Article
- Risk Factors of Synchronous Breast and Thyroid Cancer: a Controlled Multicenter Study and Review of the Literature.Materia socio-medica · 2021Review
- Risk of cancer in long-term levothyroxine users: Retrospective population-based study.Cancer science · 2021Article
- Review
- Thyroid disease is associated with an increased risk of breast cancer: a systematic review and meta-analysis.Gland surgery · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is preclinical and recent epidemiological evidence that thyroid hormone supports breast cancer. These observations raise the issue of whether management of breast cancer in certain settings should include consideration of reducing the possible contribution of thyroid hormone to the advancement of the disease. In a preliminary experience, elimination of the clinical action of endogenous L-thyroxine (T
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.