Evidence map›Paper›PMID 29441361›Full record

ArticleScience advances2018

Increased proteomic complexity in

Casimir Bamberger, Salvador Martínez-Bartolomé, Miranda Montgomery, Mathieu Lavallée-Adam, John R Yates

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Casimir BambergerDepartment of Molecular Medicine, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.ORCID 0000-0002-3830-4486
Salvador Martínez-BartoloméDepartment of Molecular Medicine, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.ORCID 0000-0001-7592-5612
Miranda MontgomeryAltman Clinical and Translation Research Institute, 9452 Medical Center Drive, University of California San Diego, La Jolla, CA 92037, USA.ORCID 0000-0002-1545-2937
Mathieu Lavallée-AdamDepartment of Biochemistry, Microbiology and Immunology and Ottawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada.ORCID 0000-0003-2124-3872
John R YatesDepartment of Molecular Medicine, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.ORCID 0000-0001-5267-1672
Scripps Research Institute · USUniversity of California San Diego Medical Center · USUniversity of Ottawa · CA

Funding

TrainingP41GM103533 · NIGMS · UNIVERSITY OF WASHINGTON · PI MACCOSS, MICHAEL · 2012 to 2021
$20.7M
TRAFFICKING AND ABETA AGGREGATIONP01AG031097 · NIA · SCRIPPS RESEARCH INSTITUTE, THE · PI KELLY, JEFFERY W · 2009 to 2013
$10.2M
Proteomic Profiling of CFTR Protein InteractionR01HL079442 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI BALCH, WILLIAM EDWARD, YATES III, JOHN R · 2005 to 2014
$4.6M
Measurement of Aberrant Protein Folds in Malignant Cells with Proteomics and Mass SpectrometryR33CA212973 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI YATES III, JOHN R · 2017 to 2019
$1.2M
NCI NIH HHS R33 CA212973NHLBI NIH HHS R01 HL079442NIA NIH HHS P01 AG031097NIGMS NIH HHS P41 GM103533
6 · The paper itself

Abstract

Cellular proteomes are thought to be optimized for function, leaving no room for proteome plasticity and, thus, evolution. However, hybrid animals that result from a viable cross of two different species harbor hybrid proteomes of unknown complexity. We charted the hybrid proteome of a viable cross between

Indexed as

Embryonic DevelopmentHybridization, GeneticProteomicsAnimalsDNA Transposable ElementsDrosophilaDrosophila ProteinsEmbryo, NonmammalianFemaleGene OntologyGenome, InsectMaleProteasome Endopeptidase ComplexProteomeSpecies SpecificityDNA Transposable ElementsDrosophila ProteinsProteasome Endopeptidase ComplexProteome

Identifiers

PMID29441361
PMCPMC5810618
OpenAlexW2792540245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.