Evidence map›Paper›PMID 29441062›Full record

ArticleFrontiers in immunology2018

TGF-β-Induced CD8

Haowen Zhong, Ya Liu, Zhenjian Xu, Peifeng Liang, Hui Yang, Xiao Zhang, Jun Zhao, Junzhen Chen, Sha Fu, Ying Tang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. TGF-β signaling mediates crosstalk between CD8Journal of biomedical science · 2026
    Article
  3. CD8Frontiers in immunology · 2026
    Review
  4. Review
  5. Article
  6. Cytotoxic T Cells: Kill, Memorize, and Mask to Maintain Immune Homeostasis.International journal of molecular sciences · 2025
    Review
  7. A donor PD-1Signal transduction and targeted therapy · 2025
    Article
  8. Review
  9. Article
  10. An angel or a devil? Current view on the role of CD8Journal of translational medicine · 2024
    Review
  11. Immunological characteristics of CD103Parasitology research · 2023
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Cytolytic CD4Frontiers in immunology · 2022
    Review
  17. CD8Frontiers in immunology · 2021
    Review
  18. Tregs in Autoimmune Uveitis.Advances in experimental medicine and biology · 2021
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Haowen ZhongDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Ya LiuDepartment of Nephrology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Zhenjian XuDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Peifeng LiangDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Hui YangDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Xiao ZhangDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Jun ZhaoDepartment of Clinical Immunology, The Third Affiliate Hospital of Sun Yat-sen University, Guangzhou, China.
Junzhen ChenDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Sha FuDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Ying TangDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Jun LvDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Julie WangDivision of Rheumatology, Milton S. Hershey Medical Center, Penn State University, Hershey, PA, United States.
Nancy OlsenDivision of Rheumatology, Milton S. Hershey Medical Center, Penn State University, Hershey, PA, United States.
Anping XuDepartment of Nephrology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Song Guo ZhengDepartment of Clinical Immunology, The Third Affiliate Hospital of Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNSun Yat-sen Memorial Hospital · CNPenn State Milton S. Hershey Medical Center · USThird Affiliated Hospital of Sun Yat-sen University · CNXuzhou Medical College · CN

Funding

Therapeutic immunoregulation mediated by TGF-??-induced iTregs in autoimmune arthR01AR059103 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JARJOUR, WAEL N · 2010 to 2020
$3.9M
NIAMS NIH HHS R01 AR059103
6 · The paper itself

Abstract

Lupus nephritis is one of most severe complications of systemic erythematosus lupus and current approaches are not curative for lupus nephritis. Although CD4

Indexed as

Immunosuppression TherapyAnimalsAntigens, CDAutoantibodiesB-LymphocytesCD8 AntigensCD8-Positive T-LymphocytesCells, CulturedFemaleGraft vs Host DiseaseImmunoglobulin GImmunotherapy, AdoptiveIntegrin alpha ChainsLupus NephritisMiceMice, Inbred C57BLalpha E integrinsAntigens, CDAutoantibodiesCD8 AntigensImmunoglobulin GIntegrin alpha ChainsTgfb1 protein, mouseTranscription FactorsTransforming Growth Factor beta1B cell responsesCD8+CD103+ iTregimmunosuppressionlupus nephritisTGF-β1

Identifiers

PMID29441062
PMCPMC5797539
OpenAlexW2792800097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.