Evidence map›Paper›PMID 29441023›Full record

ArticleFrontiers in physiology2018

Comparison of Fatty Acid and Gene Profiles in Skeletal Muscle in Normal and Obese C57BL/6J Mice before and after Blunt Muscle Injury.

Jens-Uwe Werner, Klaus Tödter, Pengfei Xu, Lydia Lockhart, Markus Jähnert, Pascal Gottmann, Annette Schürmann, Ludger Scheja, Martin Wabitsch, Uwe Knippschild

Abstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jens-Uwe WernerDepartment of General and Visceral Surgery, Ulm University Hospital, Ulm, Germany.
Klaus TödterDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Pengfei XuDepartment of General and Visceral Surgery, Ulm University Hospital, Ulm, Germany.
Lydia LockhartDepartment of General and Visceral Surgery, Ulm University Hospital, Ulm, Germany.
Markus JähnertDepartment of Experimental Diabetology, German Institute of Human Nutrition, Potsdam, Germany.
Pascal GottmannDepartment of Experimental Diabetology, German Institute of Human Nutrition, Potsdam, Germany.
Annette SchürmannDepartment of Experimental Diabetology, German Institute of Human Nutrition, Potsdam, Germany.
Ludger SchejaDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martin WabitschDivision of Pediatric Endocrinology and Diabetes, University Hospital for Pediatrics and Adolescent Medicine, Ulm, Germany.
Uwe KnippschildDepartment of General and Visceral Surgery, Ulm University Hospital, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injury and obesity are two major health burdens affecting millions of people worldwide. Obesity is recognized as a state of chronic inflammation accompanied by various co-morbidities like T2D or cardiovascular diseases. There is increasing evidence that obesity impairs muscle regeneration, which is mainly due to chronic inflammation and to excessive accumulation of lipids in adipose and non-adipose tissue. To compare fatty acid profiles and changes in gene expression at different time points after muscle injury, we used an established drop tower-based model with a defined force input to damage the

Indexed as

Alox5apApobec1C57BL/6Jfatty acidinjuryobesityskeletal muscle

Identifiers

PMID29441023
PMCPMC5797686

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.