Evidence map›Paper›PMID 29440895›Full record

ArticleInternational journal of nanomedicine2018

Biosynthesized silver and gold nanoparticles are potent antimycotics against opportunistic pathogenic yeasts and dermatophytes.

Andrea Rónavári, Nóra Igaz, Mohana Krishna Gopisetty, Bettina Szerencsés, Dávid Kovács, Csaba Papp, Csaba Vágvölgyi, Imre Miklós Boros, Zoltán Kónya, Mónika Kiricsi and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 113 citations in OpenAlex.

  1. Article
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  7. The green shield:Current research in microbial sciences · 2024
    Article
  8. Biosynthesis of gold nanoparticles by Penicillium rubens and catalytic detoxification of ochratoxin A and organic dye pollutants.International microbiology : the official journal of the Spanish Society for Microbiology · 2023
    Article
  9. Review
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  11. Potential Treatment of DermatophyteMolecules (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Andrea RónaváriDepartment of Applied and Environmental Chemistry.
Nóra IgazDepartment of Biochemistry and Molecular Biology.
Mohana Krishna GopisettyDepartment of Biochemistry and Molecular Biology.
Bettina SzerencsésDepartment of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged.
Dávid KovácsDepartment of Biochemistry and Molecular Biology.
Csaba PappDepartment of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged.
Csaba VágvölgyiDepartment of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged.
Imre Miklós BorosDepartment of Biochemistry and Molecular Biology.
Zoltán KónyaDepartment of Applied and Environmental Chemistry.
Mónika KiricsiDepartment of Biochemistry and Molecular Biology.
Ilona PfeifferDepartment of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged.
University of Szeged · HUHUN-REN Szegedi Biológiai Kutatóközpont · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpidemiologic observations indicate that the number of systemic fungal infections has increased significantly during the past decades, however in human mycosis, mainly cutaneous infections predominate, generating major public health concerns and providing much of the impetus for current attempts to develop novel and efficient agents against cutaneous mycosis causing species. Innovative, environmentally benign and economic nanotechnology-based approaches have recently emerged utilizing principally biological sources to produce nano-sized structures with unique antimicrobial properties. In line with this, our aim was to generate silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) by biological synthesis and to study the effect of the obtained nanoparticles on cutaneous mycosis causing fungi and on human keratinocytes.

methodsCell-free extract of the red yeast

resultsAntifungal studies demonstrated that the biosynthesized silver particles were able to inhibit the growth of several opportunistic

conclusionOur results emphasize the therapeutic potential of such biosynthesized nanoparticles, since their biocompatibility to skin cells and their outstanding antifungal performance can be exploited for topical treatment and prophylaxis of superficial cutaneous mycosis.

Indexed as

Antifungal AgentsBasidiomycotaCandidaCell-Free SystemCell LineDermatomycosesDrug Evaluation, PreclinicalDynamic Light ScatteringGoldHumansKeratinocytesMetal NanoparticlesMicroscopy, Electron, TransmissionSilverTrichophytonAntifungal AgentsGoldSilverantifungal activitybiological synthesisdermatophytesopportunistic pathogenic yeastssilver nanoparticlestoxicity

Identifiers

PMID29440895
PMCPMC5798539
OpenAlexW2794188423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.