Evidence map›Paper›PMID 29440690›Full record

ArticleScientific reports2018

Synthetic Whole-Cell Biodevices for Targeted Degradation of Antibiotics.

Peng-Fei Xia, Qian Li, Lin-Rui Tan, Miao-Miao Liu, Yong-Su Jin, Shu-Guang Wang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Peng-Fei XiaSchool of Environmental Science and Engineering, Shandong University, 27 Shanda Nanlu, Jinan, 250100, P.R. China.
Qian LiSchool of Environmental Science and Engineering, Shandong University, 27 Shanda Nanlu, Jinan, 250100, P.R. China.
Lin-Rui TanSchool of Environmental Science and Engineering, Shandong University, 27 Shanda Nanlu, Jinan, 250100, P.R. China.
Miao-Miao LiuDepartment of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, 205 North Mathews Ave, Urbana, IL, 61801, United States.
Yong-Su JinCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana, IL, 61801, United States.
Shu-Guang WangSchool of Environmental Science and Engineering, Shandong University, 27 Shanda Nanlu, Jinan, 250100, P.R. China. wsg@sdu.edu.cn.
Shandong University · CNUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic biology enables infinite possibilities in biotechnology via employing genetic modules. However, not many researches have explored the potentials of synthetic biology in environmental bioprocesses. In this study, we introduced a genetic module harboring the codon-optimized tetracycline degrading gene, tetX.co, into the model host, Escherichia coli, and generated a prototypal whole-cell biodevice for the degradation of a target antibiotic. Our results suggested that E. coli with the tetX.co-module driven by either the P

Indexed as

Anti-Bacterial AgentsBacterial ProteinsEscherichia coliGenetic EngineeringKineticsMixed Function OxygenasesSynthetic BiologyTetracyclineAnti-Bacterial AgentsBacterial ProteinsMixed Function OxygenasesTetracyclineTetX protein, Bacillus fragilis

Identifiers

PMID29440690
PMCPMC5811551
OpenAlexW2791774167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.